Levels of HOXB7 and miR-337 in pancreatic ductal adenocarcinoma patients

Diagnostic Pathology

Table 2 Expression of HOXB7 mRNA, protein, and miR-337 in the pancreatic ductal adenocarcinoma cases

Parameter	HOXB7 protein			HOXB7 mRNA		miR-337
	Negative (n)	Positive (n)	P value	Expression level	P value	Expression level	P value
Gender
Male	10	18	0.764	1.319 ± 0.221	0.795	0.2900 ± 0.09854	0.860
Female	5	11		1.302 ± 0.218		0.2981 ± 0.08573
Age (years)
<60	9	17	0.930	1.296 ± 0.229	0.631	0.306 ± 0.105	0.132
≥60	6	12		1.338 ± 0.203		0.274 ± 0.072
Diameter(cm)
<4	14	19	0.043*	1.259 ± 0.219	0.033*	0.305 ± 0.097	0.228
≥4	1	10		1.474 ± 0.107		0.257 ± 0.072
Location
Head	12	19	0.398	1.308 ± 0.222	0.690	0.304 ± 0.095	0.521
Body or tail	3	9		1.325 ± 0.215		0.263 ± 0.084
Differentiation
Well	6	3	0.009**	1.221 ± 0.142	0.028*	0.312 ± 0.082	0.210
Moderate	9	16		1.279 ± 0.243		0.305 ± 0.102
Poor	0	10		1.481 ± 0.084		0.245 ± 0.066
TNM stage
I or II	11	9	0.008**	1.161 ± 0.214	0.010*	0.338 ± 0.109	0.002**
III or IV	4	20		1.440 ± 0.117		0.256 ± 0.057
Nodal status
Negative	12	12	0.015*	1.199 ± 0.220	0.014*	0.330 ± 0.105	0.001**
Positive	3	17		1.450 ± 0.111		0.248 ± 0.048

ISSN: 1746-1596