Table 2 Results of meta-analysis for CTLA-4 A49G polymorphism and RA risk
From: The effect of CTLA-4 A49G polymorphism on rheumatoid arthritis risk: a meta-analysis
Groups | GG vs AA | GA vs AA | GA + GG vs AA | GG vs GA + AA | ||||
|---|---|---|---|---|---|---|---|---|
P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | |
Total | 0.009 | 1.13 (1.03, 1.23) | 0.001 | 1.19 (1.07, 1.33) | 0.001 | 1.18 (1.07, 1.29) | 0.66 | 1.03 (0.91, 1.17) |
Asians | 0.001 | 1.34 (1.15, 1.55) | 0.083 | 1.16 (0.98, 1.37) | 0.002 | 1.24 (1.08, 1.41) | 0.099 | 1.14 (0.97, 1.35) |
Caucasian | 0.991 | 1.00 (0.89, 1.12) | 0.015 | 1.19 (1.03, 1.37) | 0.042 | 1.14 (1.01, 1.29) | 0.51 | 0.93 (0.77, 1.14) |