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Table 4 Immunohistochemical features of CA and vulvar tumours for differential diagnosis

From: Cellular angiofibroma in women: a review of the literature

 

Vimentin

CD34

S-100

α-SMA

Desmin

Keratin

EMA

ER

PR

h-Caldesmon

CD-10

ACTIN

STAT-6

Agressive Angiomyxoma

3+

1+

 

1+

3+

  

3+

3+

  

1+

 

Angiomyfibroblastoma

3+

1+

 

3+

3+

  

3+

3+

  

3-/1+

 

Ffibroepithelial stromal polyp

3+

   

3+

  

1+

1+

  

1+

 

Solitary fibrous tumour

 

3+

          

3+

Smooth muscle neoplasm

    

3+

      

3+

 

Spindle cell lipoma

 

3+

           

Angiofibroma of soft tissue

 

1+

 

1+

1+

 

2+

      

Superficial myofibroblastoma of the lower female genital tract

3+

1+

3-

1+

2+

3-

3-

3+

3+

    

Cellular Angiofibroma

3+

2+

3-

2-

2-

 

3-

3+

3+

2-

 

3-

 
  1. (3+): most of cases positive; (2+): half of cases positive; (1+): few/some cases postive; (3-): typically negative; (2-): usually negative