Table 4 Univariate analysis of overall and disease-free survival rates
Survival rates Variables | Overall survival | Disease free survival | ||
|---|---|---|---|---|
P value | 95 % CI (HR) | P value | 95 % CI(HR) | |
Age ≤ 65/>65 | 0.491 | 0.506–4.124 (1.445) | 0.606 | 0.445–1.604 (0.845) |
Sex Male/Female | 0.318 | 0.046–2.711 (0.355) | 0.818 | 0.505–2.378 (1.096) |
Lymphatic permeation Yes/No | 0.584 | 0.465–3.896 (1.346) | 0.000088 | 2.161–10.087 (4.669) |
Vascular invasion Yes/No | 0.193 | 0.702–5.769 (2.012) | 0.004 | 1.352–4.805 (2.548) |
T-Classification T1-T2/ T3-T4 | 0.653 | 0.423–3.943 (1.292) | 0.060 | 0.972–4.279 (2.039) |
N-Classification (pretreatment) Yes/No | 0.082 | 0.057–1.184 (0.261) | 0.060 | 0.096–1.047 (0.317) |
Pathological lymph nodes Yes/No | 0.131 | 0.783–6.591 (2.272) | 0.003 | 1.385–5.036 (1.385) |
Grade Grade I/ Grade П/ Grade Ш | 0.459 | 0.404–1.505 (0.780) | 0.797 | 0.648–1.395 (0.951) |
Site (Oropharynx, Hypo-pharynx, Tongue, Larynx) | 0.721 | 0.640–1.904 (1.104) | 0.426 | 0.830–1.556 (1.136) |
REG-I expression Positive/Negative | 0.002 | 0.042–0.497 (0.144) | 0.000002 | 0.098–0.379 (0.193) |