| TOTAL | EGFR | KRAS | ALK | |||
---|---|---|---|---|---|---|---|
 | wt | mut | wt | mut | wt | mut | |
 | 324 (100) |  |  |  |  |  |  |
Age (range, median) | 35-88, 63 | Â | Â | Â | Â | Â | Â |
Gender | |||||||
 Male | 194 (59.9) | 183 (94.3) | 11 (5.7) | 97 (53.6) | 84 (46.4) | 80 (97.6) | 2 (2.4) |
 Female | 130 (40.1) | 90 (69.2) | 40 (30.8) | 61 (67.8) | 29 (32.2) | 40 (80.0) | 10 (20.0) |
Smoking status | |||||||
 Smokers | 147 (45.4) | 139 (94.6) | 8 (5.44) | 75 (54.3) | 63 (45.7) | 65 (95.6) | 3 (4.4) |
 Former smokers | 103 (31.8) | 92 (89.3) | 11 (10.7) | 49 (53.8) | 42 (46.2) | 37 (97.4) | 1 (2.6) |
 Never-smokers | 74 (22.8) | 42 (56.8) | 32 (43.2) | 34 (81) | 8 (19) | 18 (69.2) | 8 (30.8) |
Clinical stageb | |||||||
 I | 26 (8.0) | 22 (8.1) | 4 (7.8) | 8 (5.1) | 11 (9.2) | 7 (5.8) | 0 (0) |
 II-IIIA | 63 (19.5) | 51 (18.7) | 12 (23.5) | 31 (19.6) | 20 (16.8) | 28 (23.3) | 1 (8.3) |
 IIIB-IV | 222 (68.5) | 190 (69.6) | 32 (62.7) | 112 (70.9) | 76 (63.9) | 79 (65.8) | 10 (83.3) |