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Table 2 Cell lines with differential PD-L1 expression stained with the PD-L1 (SP263) antibody

From: Development of a programmed cell death ligand-1 immunohistochemical assay validated for analysis of non-small cell lung cancer and head and neck squamous cell carcinoma

 

Membrane

Cytoplasm

Cell line

% PD-L1+

Average intensity

% PD-L1+

Average intensity

MCF-7

0

NA

0

NA

HCT116

5

1.25

5

0.75

ACHN

50

1

0

NA

LOX

95

2.5

85

1.5

MDA-MB231

100

2.25

90

0.75

HEK293-vector

0

NA

0

NA

HEK293−

PD-L1+

5

3

5

3

HEK293−

PD-L1++

15

2.75

15

2.75

HEK293−

PD-L1+++

20

2.75

20

2.75

HEK293−

PD-L2+++

0

0

0

0

  1. NA not applicable, PD-L1 programmed cell death ligand-1, PD-L2 programmed cell death ligand-2