Fig. 2
From: Circ_0001715 accelerated lung adenocarcinoma process by the miR-1322/CANT1 axis
Knockdown of circ_0001715 inhibited the biological properties of A549 and H1299 cells. The expression of circ_0001715 was assessed by RT-qPCR (A). Clone formation assay was performed to investigate the effects of circ_0001715 knockdown on the proliferation abilities of A549 and H1299 cells (B). The effect of circ_0001715 knockdown on cell proliferation was detected by EDU assay and wound healing assay (C and D). The sphere formation efficiency of A549 and H1299 cells was detected by sphere formation assay (E). The apoptotic rates were performed and analyzed after transfection of si-circ_0001715 in A549 and H1299 cells (F). The protein levels of PCNA and Bax were detected by western blot assay in each group (G and H). The tube formation ability of HUVECs was determined by tube formation assay (I). ***p < 0.001