Fig. 3
From: Circ_0001715 accelerated lung adenocarcinoma process by the miR-1322/CANT1 axis
Circ_0001715 sponged miR-1322 in A549 and H1299 cells. The predicted binding site between miR-1322 and circ_0001715 was shown. The mutated (MUT) version of circ_0001715 is presented (A). The expression of miR-1322 was detected in LUAD tissues by RT-qPCR (B). The correlation between miR-1322 and circ_0001715 in LUAD tissues was determined by Pearson’s correlation analysis (C). Expression of miR-1322 was detected in LUAD cell lines by RT-qPCR (D). Relative luciferase activity was assessed in A549 and H1299 cells transfected with miR-1322 or miR-NC and circ_0001715 WT or circ_0001715 MUT (E and F). The relative enrichment of circ_0001715 was detected by RNA pull-down assay (G and H). ***p < 0.001