Fig. 2
From: Completing the view – histologic insights from circular AAA specimen including 3D imaging
Patient 2 sample acquisition, cutting scheme and histomorphology. CT-angiogram and photo of the un-fixed specimen and sequentially cut formalin fixed sample demonstrate the approx. acquisition site. The dotted box and circle depict the specific termination for samples (1–9; I-VIII). Histologic photos show eight (I-VIII) representative whole wall cutouts at level 3 (HE staining). Specific histologic features observed include: A fragmented elastic fibres, B collagen deposition/medial fibrosis, C calcification, D intramural bleeding, E mononuclear inflammatory cell infiltration F thrombus coverage, and G cholesterol clefts. Overall, disorganization of vascular smooth muscle cells and lamellar units is seen to various extents. All samples are presented in the same orientation (A = anterior, P = posterior, R = right, L = left, H = head, T = tail). For all histologic photos the aortic lumen is oriented upwards (scale bar 250 µm)