Fig. 3

Immunostaining results of EBV-positive and -negative tumor areas. Immunostaining results for p53 ((A) and (B)), MLH1 ((C) and (D)), PD-L1 ((E) and (F)), and ARID1A ((G)–(I)) are shown. (H) is EBV-negative tumor area with loss of ARID1A expression, whereas (I) is EBV-negative tumor area with no loss of ARID1A expression. (A), (C), (E), and (G) correspond to EBV-positive tumor area shown in Fig. 2C, and (B), (D), (F), and (H) correspond to EBV-negative tumor area shown in Fig. 2D