Fig. 2

Transbronchial biopsy revealed hyalinizing clear cell carcinoma (HCCC). Tumor cells exhibit infiltrative growth in the myxoid matrix with hyaline degeneration in the bronchial submucosa. (A). Tumor cells demonstrate eosinophilic to clear cytoplasm and light atypical round-to-oval nuclei (B). Tumor cells express CK7 (C), CK5/6 (D), and p40 (E). Ki-67 index is around 8% (F). Targeted next-generation sequencing results show EWSR1-ATF1 fusion in 14.4% of the tumor cells (G)