Fig. 1

Interaction Network of SALL4, LIN28 and KLF4 proteins obtained through the STRING platform. All observed interactions between proteins (edges connecting nodes) were obtained from selected databases (light blue line) and confirmed by text mining analysis (yellow line). LIN28A and KLF4 and SALL4 and KLF4 interactions were determined experimentally (pink line). Protein homology was demonstrated between SALL4 and KLF4 (purple line), and coexpression between LIN28A and SALL4 was computationally observed from transcript–transcript interactions (black line)