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Table 4 Composite Immunophenotypic Surrogates for Molecular Subtype in MUC

From: Morphology, immunohistochemistry characteristics, and clinical presentation of microcystic urothelial carcinoma: a series of 10 cases

 

Composite Immunophenotype

Classification

Total (n = 10), No. (%)

Positive (IHC Score > 4)

Negative (IHC Score ≤ 4)

Dadhania et al. [12]

GATA3

CK5/6

Luminal

1(10)

CK5/6

GATA3

Basal

0(0)

GATA3

CK14

Luminal

10(100)

CK14

GATA3

Basal

0 (0)

Rebouissou et al. [10]

FOXA1

CK5/6

Non–basal-like

1(10)

CK5/6

FOXA1

Basal-like

1(10)

Sjödahl et al. [11]

CK5/6 and CK14

FOXA1 and GATA3

Basal/SCC-like

0(0)

Johnson et al. [9]

FOXA1

CK14

Luminal

9(90)