Pathologist-trained machine learning classifiers developed to quantitate celiac disease features differentiate endoscopic biopsies according to modified marsh score and dietary intervention response

Table 3 Evaluation of paired-biopsy samples

Matched Pair	Modified Marsh Score			Continuous Machine Learning Score
Matched Pair	Pre- Biopsy	Post- Biopsy	Manual Score Response	Pre- Biopsy	Post- Biopsy	Alignment with Manual Score
1	3b	0	Yes	3.95	1.63	Yes
2	3a	0	Yes	0.82	−0.20	Yes
3	3b	0	Yes	2.44	0.11 4	Yes
4	3b	1	Yes	2.22	0.21	Yes
5	3a	3a	No	2.46	3.49	No
6	3b	0	Yes	3.78	−0.21	Yes
7	3b	0	Yes	2.85	1.52	Yes
8	3a	0	Yes	2.65	0.02	Yes
9	3b	0	Yes	2.44	1.15	Yes
10	1	0	Yes	1.57	0.78	Yes
11	3b	3a	Yes	3.48	1.65	Yes
12	3b	0	Yes	3.56	0.61	Yes
13	3b	1	Yes	2.80	1.51	Yes
14	3a	0	Yes	3.56	0.56	Yes
15	3a	0	Yes	1.27	0.55	Yes
16	2	1	Yes	2.28	0.93	Yes
17	3b	0	Yes	2.36	1.65	Yes
18	3b	0	Yes	4.28	0.40	Yes
19	3a	0	Yes	2.60	0.00	Yes
20	3b	0	Yes	1.70	0.98	Yes
21	3c	3b	Yes	3.71	1.70	Yes
22	3a	0	Yes	1.80	0.78	Yes
23	3b	0	Yes	3.06	−1.23	Yes
24	3b	0	Yes	2.96	0.71	Yes
25	3a	0	Yes	2.51	0.47	Yes
26	3b	0	Yes	3.38	0.87	Yes
27	3b	3a	Yes	3.02	1.96	Yes
28	3b	0	Yes	3.13	1.13	Yes

ISSN: 1746-1596