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Fig. 2 | Diagnostic Pathology

Fig. 2

From: Response to PD-1 inhibitor in SMARCB1‑deficient undifferentiated rectal carcinoma with low TMB, proficient MMR and BRAF V600E mutation: a case report and literature review

Fig. 2

Pathological findings. A, B The tumor, measuring 6.5 cm × 6.2 cm × 1.5 cm, occupied 3/4 of the rectal lumen. It presented as a well-demarcated mass lesion with central deep ulceration. The cut surface showed a grayish-white or grayish-yellow solid tumor with central hemorrhage and necrosis. The tumor had invaded through the muscularis propria into the peri-rectal tissues. C-G Histopathological findings revealed that the tumor cells had poor connectivity, eosinophilic cytoplasm and a polymorphic nucleus. H Metastasis was observed in regional lymph nodes

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Diagnostic Pathology

ISSN: 1746-1596

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