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Fig. 4 | Diagnostic Pathology

Fig. 4

From: Recognizing puzzling PD1 + infiltrates in marginal zone lymphoma by integrating clonal and mutational findings: pitfalls in both nodal and transformed splenic cases

Fig. 4

Morphologic and immunophenotypic findings of lymphoma from April 2017 splenectomy in Case 3. Spleen structure replaced neoplastic lymphoid cells with necrosis in (A); nodular growth pattern can be seen easily in (B), comprising small- to medium-sized cells in (C); by immunostaining, cells in the center region of nodules were CD3 positive (D), cells in the peripheral region of the nodules were CD20 positive (E), and the Ki67 index was approximately 35% in the center and 10% in the periphery of the nodules (F)

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