Patient characteristic | HR status | P | ||||
---|---|---|---|---|---|---|
ER + /PR +  | ER + /PR- | ER-/PR +  | ER-/PR- | |||
N (%) | N (%) | N (%) | N (%) | |||
Total | Â | 371 (42.2) | 113 (12.9) | 11 (1.3) | 384 (56.4) | Â |
Age at diagnosis | 20–40 | 74 (19.9) | 19 (16.8) | 4 (36.4) | 63 (16.4) | 0.533 |
 | 41–60 | 257 (69.3) | 81 (71.7) | 7 (63.6) | 276 (71.9) |  |
 | 61–80 | 40 (10.8) | 13 (1.5) | 0 (0) | 45 (11.7) |  |
Surgical methods | BCS | 21 (5.7) | 4 (3.5) | 1 (9.0) | 10 (2.6) | 0.153 |
 | M | 350 (94.3) | 109 (96.5) | 10 (91.0) | 374 (97.4) |  |
Menstruatio | Yes | 137 (36.9) | 70 (61.9) | 1 (9.0) | 212 (55.2) |  < 0.001 |
 | No | 234 (63.1) | 43 (38.1) | 10 (91.0) | 172 (44.8) |  |
BMI |  ≤ 18.5 | 6 (1.6) | 4 (3.5) | 0 (0) | 9 (2.3) | 0.090 |
 | 18.5–24 | 160 (43.1) | 48 (42.5) | 8 (72.7) | 182 (47.4) |  |
 | 24–30 | 183 (49.3) | 58 (48.7) | 1 (9.1) | 167 (43.5) |  |
 |  ≥ 30 | 22 (6.0) | 3 (2.7) | 2 (18.2) | 26 (6.8) |  |
Clinical T stage | 1 | 45 (12.1) | 17(15.0) | 1 (9.1) | 44 (11.4) | 0.588 |
 | 2 | 277 (74.6) | 81 (71.6) | 8 (72.7) | 271 (70.5) |  |
 | 3 | 49 (13.3) | 15 (13.4) | 2 (18.2) | 69 (18.1) |  |
Clinical N stage | 0 | 52 (14.0) | 11 (9.7) | 2 (18.1) | 45 (11.7) | 0.373 |
 | 1 | 218 (58.7) | 62 (54.8) | 7 (63.8) | 212 (55.2) |  |
 | 2 | 41 (11.2) | 18 (16.1) | 0 (0) | 41 (10.6) |  |
 | 3 | 60 (16.1) | 22 (19.4) | 2 (18.1) | 86 (22.5) |  |
HER-2 | Positive | 70 (18.9) | 43 (38.1) | 3 (37.3) | 218 (56.8) |  < 0.001 |
 | Negative | 301 (81.1) | 70 (61.9) | 8 (62.7) | 166 (43.2) |  |
KI67 |  ≤ 15 | 171 (46.1) | 36 (29.2) | 3 (37.3) | 101 (26.3) |  < 0.001 |
 |  > 15 | 200 (53.9) | 77 (70.8) | 8 (62.7) | 283 (73.7) |  |
P53 | 0 | 209 (56.3) | 57 (50.4) | 4 (36.3) | 191 (49.7) |  < 0.001 |
 | 1 | 123 (33.1) | 34 (30.0) | 4 (36.3) | 48 (12.5) |  |
 | 2 | 24 (6.6) | 12 (10.8) | 1 (9.0) | 59 (15.3) |  |
 | 3 | 15 (4.0) | 10 (8.8) | 2 (18.4) | 86 (22.5) |  |
Histological grade | 0–1 | 109 (29.4) | 39 (34.5) | 3 (37.3) | 175 (45.6) |  < 0.001 |
 | 2 | 250 (67.4) | 65 (57.5) | 6 (44.6) | 130 (33.9) |  |
 | 3 | 12 (3.2) | 9 (8.0) | 2 (18.1) | 79 (20.5) |  |
Stage | I | 7 (1.8) | 0 (0) | 0 (0) | 6 (1.6) | 0.359 |
 | II | 238 (64.2) | 67 (59.3) | 7 (63.6) | 220 (58.4) |  |
 | III | 126 (34.0) | 46 (40.7) | 4 (36.4) | 158(40.0) |  |
Histological type | IDC | 279 (75.2) | 75 (66.4) | 9 (82.0) | 219 (57.0) |  < 0.001 |
 | ILC | 43 (11.6) | 15 (13.3) | 1 (9.0) | 53 (13.8) |  |
 | Others | 49 (12.2) | 23 (20.3) | 1 (9.0) | 112 (29.2) |  |