Patient characteristic | OS | BCSS | |||||
---|---|---|---|---|---|---|---|
Hazard Ratio | CI (95%) | P | Hazard Ratio | CI (95%) | P | ||
Age at diagnosis | 20–30 | Ref |  |  | Ref |  |  |
 | 31–40 | 0.796 | 0.611–1.038 | 0.092 | 0.859 | 0.644–1.145 | 0.300 |
 | 41–50 | 0.482 | 0.374–0.622 |  < 0.001 | 0.444 | 0.336–0.623 |  < 0.001 |
 | 51–60 | 0.592 | 0.463–0.765 |  < 0.001 | 0.473 | 0.359–0.623 |  < 0.001 |
 | 61–70 | 0.744 | 0.580–0.955 | 0.020 | 0.396 | 0.300–0.521 |  < 0.001 |
 | 71–80 | 1.517 | 1.182–1.947 | 0.001 | 0.542 | 0.411–0.714 |  < 0.001 |
Race | White | Ref | Â | Â | Ref | Â | Â |
 | Black | 1.728 | 1.627–1.835 |  < 0.001 | 2.149 | 1.984–2.327 |  < 0.001 |
 | Others | 0.805 | 0.752–0863 |  < 0.001 | 0.931 | 0.848–1.023 | 0.136 |
Histological grade | 1 | Ref | Â | Â | Â | Â | Â |
 | 2 | 1.435 | 1.351–1.524 |  < 0.001 | 2.471 | 2.202–2.772 |  < 0.001 |
 | 3 | 2.342 | 2.206–2.485 |  < 0.001 | 6.389 | 5.721–7.135 |  < 0.001 |
T stage | 1 | Ref | Â | Â | Â | Â | Â |
 | 2 | 1.994 | 1.906–2.085 |  < 0.001 | 3.830 | 3.573–4.105 |  < 0.001 |
 | 3 | 3.214 | 3.000–3.442 |  < 0.001 | 7.738 | 7.075–8.464 |  < 0.001 |
 | 4 | 7.047 | 6.467–7.680 |  < 0.001 | 17.291 | 15.543–19.236 |  < 0.001 |
N stage | 0 | Ref | Â | Â | Â | Â | Â |
 | 1 | 1.750 | 1.666–1.839 |  < 0.001 | 3.188 | 2.977–3.414 |  < 0.001 |
 | 2 | 3.018 | 2.814–3.237 |  < 0.001 | 6.288 | 5.759–6.866 |  < 0.001 |
 | 3 | 4.921 | 4.553–5.318 |  < 0.001 | 11.135 | 10.14–12.220 |  < 0.001 |
ER | Negative | Ref | Â | Â | Â | Â | Â |
 | Positive | 0.528 | 0.503–0.553 |  < 0.001 | 0.337 | 0.317–0.358 |  < 0.001 |
PR | Negative | Ref | Â | Â | Â | Â | Â |
 | Positive | 0.561 | 0.543–0.591 |  < 0.001 | 0.361 | 0.341–0.383 |  < 0.001 |
HER-2 | Negative | Ref | Â | Â | Â | Â | Â |
 | Positive | 0.990 | 0.934–1.050 | 0.737 | 1.158 | 1.070–1.253 |  < 0.001 |
Stage | I | Ref | Â | Â | Â | Â | Â |
 | II | 1.784 | 1.702–1.870 |  < 0.001 | 3.899 | 3.599–4.224 |  < 0.001 |
 | III | 4.306 | 4.085–4.538 |  < 0.001 | 12.911 | 11.901–14.005 |  < 0.001 |
Histological type | IDC | Ref | Â | Â | Â | Â | Â |
 | ILC | 1.015 | 0.949–1.084 | 0.672 | 1.009 | 0.918–1.109 | 1.009 |
 | Others | 0.941 | 0.867–1.021 | 0.143 | 0.894 | 0.794–1.008 | 0.894 |
HR status | ER + /PR +  | Ref |  |  |  |  |  |
 | ER + /PR- | 1.508 | 1.420–1.601 |  < 0.001 | 2.163 | 1.993–2.348 |  < 0.001 |
 | ER-/PR +  | 2.036 | 1.721–2.409 |  < 0.001 | 3.435 | 2.798–4.217 |  < 0.001 |
 | ER-/PR- | 2.020 | 1.922–2.124 |  < 0.001 | 3.419 | 3.201–3.652 |  < 0.001 |