Patient characteristic | All patients | χ2 | P | ||||
---|---|---|---|---|---|---|---|
pCR(n = 144) | NpCR(n = 735) | ||||||
N | % | N | % | ||||
Age |  ≤ 40 | 30 | 20.8 | 130 | 17.7 | 0.801 | 0.371 |
 |  > 40 | 114 | 79.2 | 605 | 82.3 |  |  |
Surgical methods | BCS | 4 | 27.8 | 32 | 4.4 | 0.761 | 0.383 |
 | M | 140 | 72.2 | 703 | 95.6 |  |  |
Menstruatio | Yes | 72 | 50.0 | 387 | 52.7 | 0.340 | 0.560 |
 | No | 72 | 50.0 | 348 | 47.3 |  |  |
BMI |  ≤ 18.5 | 1 | 0.6 | 18 | 2.4 | 3.488 | 0.322 |
 | 18.5–24 | 73 | 50.7 | 325 | 44.2 |  |  |
 | 24–30 | 61 | 42.4 | 348 | 47.3 |  |  |
 |  ≥ 30 | 9 | 6.3 | 44 | 6.1 |  |  |
Clinical T stage | 1 | 31 | 21.5 | 76 | 10.3 | 18.043 |  < 0.001 |
 | 2 | 101 | 70.1 | 536 | 73.0 |  |  |
 | 3 | 12 | 8.4 | 123 | 16.7 |  |  |
Clinical N stage | 0 | 26 | 18.1 | 84 | 11.4 | 5.099 | 0.165 |
 | 1 | 79 | 54.9 | 420 | 57.1 |  |  |
 | 2 | 14 | 9.7 | 86 | 11.7 |  |  |
 | 3 | 25 | 17.3 | 145 | 19.8 |  |  |
ER | Positive | 50 | 34.7 | 434 | 59.0 | 28.795 |  < 0.001 |
 | Negative | 94 | 65.3 | 301 | 41.0 |  |  |
PR | Positive | 32 | 22.2 | 350 | 47.6 | 31.607 |  < 0.001 |
 | Negative | 112 | 77.8 | 385 | 52.4 |  |  |
HER-2 | Positive | 84 | 58.3 | 250 | 34.0 | 31.139 |  < 0.001 |
 | Negative | 60 | 41.7 | 485 | 64.0 |  |  |
KI67 |  ≤ 15 | 32 | 22.2 | 267 | 36.3 | 10.672 |  < 0.001 |
 |  > 15 | 112 | 77.8 | 468 | 63.7 |  |  |
HR status | ER + /PR +  | 31 | 21.5 | 340 | 46.3 | 35.105 |  < 0.001 |
 | ER + /PR- | 19 | 13.2 | 94 | 12.8 |  |  |
 | ER-/PR +  | 1 | 0.7 | 10 | 1.4 |  |  |
 | ER-/PR- | 93 | 64.6 | 291 | 39.5 |  |  |
P53 | 0 | 66 | 45.8 | 395 | 53.8 | 6.215 | 0.102 |
 | 1 | 34 | 23.6 | 175 | 23.8 |  |  |
 | 2 | 17 | 11.8 | 79 | 10.7 |  |  |
 | 3 | 27 | 19.8 | 86 | 11.7 |  |  |
Histological type | IDC | 0 | 0 | 583 | 79.3 | 418.91 |  < 0.001 |
 | ILC | 0 | 0 | 21 | 2.9 |  |  |
 | DCIS | 30 | 20.8 | 3 | 0.4 |  |  |
 | Others | 114 | 79.2 | 128 | 17.4 |  |  |
Histological grade | 0–1 | 144 | 100 | 183 | 12.5 | 290.70 |  < 0.001 |
 | 2 | 0 | 0 | 451 | 61.4 |  |  |
 | 3 | 0 | 0 | 101 | 26.1 |  |  |
Stage | I | 0 | 0 | 13 | 1.8 | 10.105 | 0.006 |
 | II | 103 | 71.5 | 429 | 58.4 |  |  |
 | III | 41 | 28.5 | 293 | 39.8 |  |  |