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Table 1 Correlations between ACAT2 expression and the clinicopathological characteristics

From: High-expressed ACAT2 predicted the poor prognosis of platinum-resistant epithelial ovarian cancer

  

ACAT2 expression

  
 

Total

(n = 77)

Low (n = 26)

High (n = 51)

χ2 value

P

Mean age at diagnosis (years)

   

1.08

0.298

< 55

41

16

25

  

≥ 55

36

10

26

  

FIGO stage

   

7.01

0.030

I

3

3

0

  

II

2

0

2

  

III - IV

72

23

49

  

Weight (kg)

   

0.06

0.812

< 55

40

14

26

  

≥ 55

37

12

25

  

Height (cm)

   

2.32

0.127

< 158

36

9

27

  

≥ 158

41

17

24

  

Pathological type

   

0.99

0.610

Serous carcinoma

72

24

48

0.232

0.630

High-grade

62

20

42

  

Low-grade

10

4

6

  

Mix serous carcinoma

4

2

2

  

Clear cell carcinoma

1

0

1

  

Grades

   

0.20

0.655

High

67

22

45

  

Low

10

4

6

  

Tumor size(cm)

   

<0.01

0.949

< 8.5

47

16

31

  

≥ 8.5

30

10

20

  

Chemo-response

   

4.17

0.041

Sensitivity

47

20

27

  

Resistance

30

6

24

  

CA125 (U/ml)

   

<0.01

0.942

< 2475

59

19

40

  

≥ 2475

16

5

11

  

HE4(pmol/L)

   

2.56

0.278

< 733

40

11

29

  

≥ 733

29

13

16

  

Miss

8

2

6

  

Ascites volume (ml)

   

2.84

0.092

< 1492

37

9

28

  

≥ 1492

40

17

23

  

Surgical satisfaction

   

3.98

0.136

R0

12

7

5

  

R1

50

14

36

  

R2

15

5

10

  
  1. Note: ACAT2: Acetyl-CoA acetyltransferase 2; FIGO: International Federation of Gynecology and Obstetrics; CA125: carbohydrate antigen 125; HE4: human epididymal protein 4