Table 2 Prognostic factors for platinum-free interval (PFI), progression-free survival (PFS) and overall survival (OS) selected by kaplan-meier analysis

Mean age at diagnosis (years)

< 55

11.57

8.18–14.96

1.25

0.263

17.19

13.89–20.50

1.17

0.280

47.22

38.09–56.36

1.56

0.211

≥ 55

9.18

5.96–12.40

14.71

11.50-17.92

37.12

29.61–44.63

FIGO stage

I-II

19.13

11.45–26.82

8.79

0.012

24.03

16.83–31.24

13.08

0.001

56.61

42.78–70.43

5.08

0.079

III

10.37

7.84–12.90

16.11

13.63–18.59

43.42

36.40-50.44

IV

2.85

0.00-6.42

7.03

2.76–11.29

24.76

10.36–39.17

Weight (kg)

< 55

12.08

8.71–15.44

1.63

0.202

17.81

14.58–21.04

1.74

0.187

45.97

37.24–54.71

0.49

0.486

≥ 55

8.69

5.48–11.91

14.11

10.86–17.36

38.2

30.38–46.02

Height (cm)

< 158

11.01

8.42–13.60

0.11

0.744

16.19

13.70-18.68

0.00

0.986

43.9

34.51–53.29

0.09

0.761

≥ 158

9.96

6.15–13.77

15.90

12.11–19.68

42.73

33.84–51.61

Pathological type

Serous carcinoma

10.86

8.38–13.33

4.08

0.130

16.45

14.02–18.89

0.04

6.300

45.00

38.31–51.68

10.99

0.004

Mix serous carcinoma

3.78

0.00-8.18

9.03

5.16–12.90

20.25

9.68–30.82

Clear cell carcinoma

7.83

7.83–7.83

13.73

13.73–13.73

17.00

17.00–17.00

Grades

High

9.77

7.49–12.05

2.09

0.148

15.38

13.15–17.62

2.17

0.141

41.85

34.89–48.81

1.16

0.281

Low

15.01

5.30-24.72

20.39

10.71–30.06

55.59

36.96–74.21

Tumor size (cm)

< 8.5

10.83

7.48–14.19

0.39

0.531

16.33

13.02–19.64

0.19

0.664

43.78

34.89–52.66

0.02

0.887

≥ 8.5

9.85

6.83–12.87

15.57

12.60-18.53

42.99

33.92–52.06

Chemo-response

Sensitivity

15.95

13.09–18.81

102.72

< 0.001

21.19

18.41–23.97

65.09

< 0.001

51.08

43.34–58.82

12.60

< 0.001

Resistance

1.83

0.98–2.69

7.95

6.31–9.59

26.65

20.61–32.68

CA125 (U/ml)

< 2475

11.24

8.69–13.79

1.67

0.197

16.65

14.13–19.17

1.29

0.255

42.60

35.51–49.69

0.18

0.676

≥ 2475

7.45

1.75–13.16

13.68

8.05–19.31

40.47

30.29–50.66

HE4 (pmol/L)

< 733

11.66

7.95–15.36

1.73

0.422

17.32

13.71–20.93

1.62

0.446

50.94

40.55–61.32

7.67

0.022

≥ 733

9.42

6.17–12.68

14.89

11.64–18.13

38.95

31.43–46.48

Miss

8.14

2.46–13.82

13.75

7.86–19.64

25.03

11.00-39.07

Ascites volume (ml)

< 1492

12.13

8.79–15.46

3.92

0.048

17.51

14.20-20.82

3.19

0.074

49.41

40.32–58.50

6.14

0.013

≥ 1492

8.09

5.05–11.13

13.95

10.98–16.92

32.63

26.88–38.39

Surgical satisfaction

R0

22.67

16.30-29.04

12.73

0.002

26.79

20.74–32.83

10.68

0.005

64.98

52.18–77.79

7.36

0.025

R1

7.7

5.70–9.71

13.54

11.42–15.66

37.23

30.14–44.33

R2

9.83

3.38–16.28

15.74

9.19–22.29

36.99

26.26–47.72

ACAT2 expression

Low

14.13

9.32–18.94

4.06

0.044

19.79

15.23–24.35

4.24

0.039

52.40

41.47–63.33

4.04

0.044

High

8.57

6.13–11.02

14.12

11.63–16.60

36.89

30.31–43.47