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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Diagnostic potential of NRG1 in benign nerve sheath tumors and its influence on the PI3K-Akt signaling and tumor immunity

Fig. 3

Selection of disease-specific genes for predicting BNST occurrence. A Construction of the intersection gene PPI network. B Visualization of the PPI network of hub genes and their adjacent nodes using Cytoscape software. C LASSO analysis results: the x-axis represents log(λ) values, and the y-axis represents Binomial Deviance. The graph shows the number of genes retained when using different log(λ) values, and the log(λ) value and number of retained genes corresponding to the optimal Binomial Deviance value are marked with dashed lines. D The intersection of candidate genes obtained through LASSO analysis and PPI protein interaction screening is shown by a Venn diagram. E Validation through the merged dataset demonstrates that NRG1 has a higher predictive value in BNST diagnosis

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Diagnostic Pathology

ISSN: 1746-1596

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