Table 4 Multivariate analysis of factors related to CLNM in 2384 PTC patients [n (%)]
Influencing factors | Group | Number of cases | Is the central lymph node metastatic | OR | OR95% CI | P-value | |
|---|---|---|---|---|---|---|---|
Yes | No | ||||||
Gender | |||||||
Male | 353 | 236 (66.9) | 117 (33.1) | 5.294 | 3.768–7.438 | < 0.001 | |
Female | 2031 | 938 (46.2) | 1093 (53.8) | 1.000 | |||
Age (years) | < 0.001 | ||||||
≤ 30 | 151 | 127 (84.1) | 24 (15.9) | 3.188 | 1.963–5.176 | < 0.001 | |
30–55 | 1694 | 781 (46.1) | 913 (53.9) | 1.398 | 0.905–1.945 | 0.078 | |
>55 | 539 | 266 (49.4) | 273 (50.6) | 1.000 | |||
Lesion size (cm) | < 0.001 | ||||||
≤ 0.5 | 1015 | 356 (35.1) | 659 (64.9) | 1 | |||
0.5- 1 | 905 | 454 (50.2) | 451 (49.8) | 2.924 | 2.227–3.841 | < 0.001 | |
1–2 | 347 | 258 (74.4) | 89 (25.6) | 4.000 | 2.801–5.711 | < 0.001 | |
2–4 | 107 | 97 (90.7) | 10 (9.3) | 6.740 | 2.801–10.862 | < 0.001 | |
>4 | 10 | 9 (90.0) | 1 (10.0) | 5.168 | 1.218–21.930 | 0.026 | |
Multifocal | Single | 1573 | 536 (34.1) | 1137 (72.3) | 1.000 | ||
Many | 811 | 638 (78.7) | 173 (21.3) | 0.667 | 0.515–0.863 | 0.002 | |