Table 4 Historical control autopsy brain cases
From: Acute neutrophilic vasculitis (leukocytoclasia) in 36 COVID-19 autopsy brains
Case no. | Age (yr)/Sex | Major clinical and autopsy diagnoses; positive blood cultures | Ventilator use (da) | Anti-coagulation treatment | Karyorrhectic CNS small blood vessels | Hospital survival (da) |
|---|---|---|---|---|---|---|
1 | 61/M | HTN, DM2, obesity, DLE, lung abscess; diphtheroids | Acutely | Enoxaparin | Yes | 3 |
2 | 64/F | HTN, DM, COPD, IHD, obesity, cancer; Acinetobacter baumannnii, diphtheroids | 2 | Enoxaparin | No | 2 |
3 | 70/F | HTN, obesity, clinical remote stroke; Klebsiella pneumoniae | N/R | Warfarin, enoxaparin | Yes | 4 |
4 | 53/F | HTN, DM2, IHD, obesity; Clostridium perfringens, α-hemolytic Streptococcus | Acutely | N/R | Yes | 0.2 |
5 | 66/F | HTN, DM, IHD, obesity, remote stroke NCH; Enterococcus faecalis, Pseudomonas mirabilis | N/R | Aspirin, apixaban | Yes | 1 |
6 | 52/M | HTN, DM, IHD, CRD, pancreatitis; Klebsiella pneumoniae | Acutely | N/R | No | 9 |
7 | 61/F | HTN, obesity, cancer, PE; Enterococcus gallinarum | E/P | Heparin, enoxaparin | Yes | 11 |
8 | 69/F | HTN, BD, basal ganglia hemorrhage; K. pneumoniae | Acutely | N/R | No | 0.2 |
9 | 65/F | HTN, COPD, focal frontal lobe perivascular brain hemorrhage; diphtheroids | Acutely | Heparin | No | 0.04 |
10 | 57/M | DM2, PE | Acutely | Enoxaparin, tPA | No | 2 |
11 | 35/M | Obesity, epilepsy, frontotemporal FCD | Acutely | N/R | No | 0.04 |
12 | 38/M | Obesity, aortic dissection, PE | N/R | Heparin, tPA | Yes | 12 |
13 | 39/M | HCV, Lyme disease, SAD, CAH, cervical spinal epidural abscesses; Staphylococcus aureus | N/R | N/R | Yes | 6 |
14 | 47/F | HTN, DM2, IHD, COPD, obesity, congenital heart disease | N/R | tPA | No | 0.6 |
15 | 86/F | HTN, cancer, CRD, aortic dissection, small remote basal ganglia infarcts; Staphylococcus aureus, α-hemolytic Streptococcus | Acutely | N/R | No | 0.02 |
16 | 91/F | HTN, IHD, CRD, BD, schizophrenia, stroke NCH; K. pneumoniae, Escherichia coli, Clostridium perfringens | Acutely | N/R | Yes | 0.04 |
17 | 63/M | HTN, IHD, BD, DVT, PE, 0.5-cm left frontal remote infarct | E/P | Enoxaparin | Yes | 11 |
18 | 59/F | HTN, arthritis, gastric ulcers, sepsis, intestinal and gall bladder necrosis; Candida glabrata | E/P | N/R | No | 2 |
19 | 58/M | HTN, cancer | N/R | Heparin | No | 8 |
20 | 60/M | Obesity, SAD, hepatic cirrhosis, thrombocytopenia; Candida albicans | 2 | Aspirin | No | 4 |
21 | 71/M | HTN, DM2, IHD, obesity, cancer, CRD | Acutely | Aspirin | No | 6 |