Neuroendocrine and squamous cell phenotypes of NUT carcinoma are potential diagnostic pitfalls that discriminating it from mimickers, such as small cell and squamous cell carcinoma

Table 4 Expression levels of each antibody evaluated using H-scores

Case	NUT	CGA	SYN	CD56	TTF-1	P40	CK5/6	INSM1	ASCL1	BCL2	ProGRP
NUT carcinoma (n = 8)
1	270	0	NE	NE	0	NE	0	40	0	0	0
2	285	0	3	0	0	0	0	50	0	20	0
3	300	0	0	0	0	40	60	60	0	2	0
4	285	0	80	0	0	0	0	75	0	180	0
5	285	0	0	0	0	300	285	50	0	0	0
6	NE	0	0	0	NE	NE	NE	NE	NE	NE	NE
7	NE	NE	NE	NE	NE	NE	NE	NE	NE	NE	NE
8	300	0	0	3	0	300	220	50	0	30	0
Basaloid squamous cell carcinoma (n = 8)
1	0	0	0	0	0	300	300	0	0	300	0
2	0	0	0	0	0	210	300	0	0	100	0
3	0	0	0	0	0	300	300	5	0	300	0
4	0	0	0	0	0	300	300	0	0	300	0
5	0	0	0	0	0	300	300	0	0	300	0
6	0	0	0	20	0	30	160	0	0	300	0
7	0	0	0	150	0	300	270	0	0	300	0
8	0	1	0	0	0	300	300	60	0	300	0
Small cell lung carcinoma (n = 13)
1	0	10	180	300	300	0	0	160	160	300	0
2	0	5	200	300	300	0	0	255	300	300	140
3	0	30	100	300	180	80	0	300	5	5	0
4	0	0	285	300	300	0	0	120	90	270	100
5	0	0	180	300	300	0	0	300	0	285	0
6	0	5	80	300	190	0	0	270	270	300	20
7	0	10	285	300	300	0	0	285	140	300	120
8	0	120	150	300	240	0	0	255	285	300	50
9	0	55	300	300	300	0	0	120	90	300	25
10	0	0	60	300	300	0	0	150	240	300	0
11	0	0	0	0	0	0	2	30	0	300	0
12	0	20	300	300	300	0	0	285	160	300	50
13	0	270	300	160	300	0	0	120	270	300	0

ISSN: 1746-1596