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Table 1 Clinical characteristics of OSCC in adolescents

From: High incidence of HPV infection in minors with oral squamous cell carcinoma

Case no.

Age, y/sex

Location

Clinical manifestation

Size/cm

Management

LN metastasis

Radiotherapy/chemotherapy

Follow-up

TNM stage

1

6/F

Lower gingiva

Mass

1.5 × 1.5 × 1.5

ER + Segmental mandibulectomy + CLND

No

Yes

NR, 3 mo

T2N0M0

2

14/M

Upper gingiva

Ulceration

5 × 3 × 3

ER + Hemi-maxillectomy + CLND

Yes

Yes

1st R, 1 y; 2nd NR

T3N2bM0

3

14/M

Right mandible

Mass

3 × 2.5 × 2

ER + Segmental mandibulectomy + CLND

No

No

NR, 2 y

T3N0M0

4

3/F

Submandibular triangle

Mass

7 × 8 × 8

Enucleation + CLND

No

N/A

/

T3N0M0

5

14/F

Tongue

Ulceration

3.5 × 2.5 × 1.5

ER + CLND

No

N/A

NR, 18 mo

T2N0M0

6

8/F

Left maxilla

Mass

N/A

ER + Hemi-maxillectomy + CLND

No

N/A

NR, 5 y

N/A

  1. F female, M male, y year, mo month, ER extended resection, CLND cervical lymph node dissection, LN lymph node metastasis, R recurrence, NR no recurrence, NA not available, / loss to follow-up