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Fig. 2 | Diagnostic Pathology

Fig. 2

From: Cerebrospinal fluid and blood exosomes as biomarkers for amyotrophic lateral sclerosis; a systematic review

Fig. 2

The ALS disease pathological signaling pathway. MFG-E8: milk fat globule-EGF factor 8, PGRN: Progranulin, MCP-1: macrophage chemoattractant protein-1, MIP-1β: macrophage inflammatory protein-1β, ROS: reactive oxygen species, SOD1: Superoxide dismutase 1, FUS: Fused in sarcoma, TDP-43: TAR DNA-binding protein 43, NFL: neurofilament light, NFH: neurofilament heavy, DPRs: dipeptide repeat proteins

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