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Fig. 1 | Diagnostic Pathology

Fig. 1

From: PKM2 promotes lymphatic metastasis of hypopharyngeal carcinoma via regulating epithelial-mesenchymal transition: an experimental research

Fig. 1

Expression and prognostic value analysis of PKM2 in clinical specimens. (A) Box plots show the PKM2 expression levels in 519 HNSCCs and 44 normal tissues by GEPIA2 online website. (B) The OS probability of HNSCC patients with high vs. low expression of PKM2 according to TCGA data. (C) qRT-PCR analysis of the expression of PKM2. (D,E) Western blotting analysis of the expression of PKM2. (F) Immunohistochemical staining for PKM2. (G) Kaplan-meier survival curve of of risk factor for lymphatic metastasis. (H) Kaplan-meier survival curve of of risk factor for PKM2 expression. L, lymphatic metastasis patients’ tumor tissue; NL, non-lymphatic metastasis patients’ tumor tissue; N, Normal tissue adjacent to the carcinoma; NC, negative control. *P < 0.05, **P < 0.01, ***P < 0.001

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Diagnostic Pathology

ISSN: 1746-1596

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