Skip to main content
Fig. 4 | Diagnostic Pathology

Fig. 4

From: PKM2 promotes lymphatic metastasis of hypopharyngeal carcinoma via regulating epithelial-mesenchymal transition: an experimental research

Fig. 4

PKM2 regulates tumor growth and lymphatic metastasis in vivo. (A) Anatomy of foot-pad primary tumors and metastatic LNs in nude mice, red arrow indicates foot-pad primary tumors, yellow arrow indicates metastatic LNs. (B) Tumor growth graphs of nude mice. (C) Representative images of enucleated footpad tumors for the indicated groups. (D) Representative images of enucleated popliteal LNs for the indicated groups. (E,F) The weight and volume of footpad tumors for the relevant groups. (G,H) The weight and volume of LNs for the relevant groups. (I) Typical H&E-stained micrographs of primary tumors and metastatic LNs in vivo. (J) Percentages of lymphatic metastasis in animal models. *P < 0.05, **P < 0.01, ***P < 0.001

Back to article page

Diagnostic Pathology

ISSN: 1746-1596

Contact us