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Fig. 5 | Diagnostic Pathology

Fig. 5

From: PKM2 promotes lymphatic metastasis of hypopharyngeal carcinoma via regulating epithelial-mesenchymal transition: an experimental research

Fig. 5

PKM2 promotes lymphatic metastasis through EMT induction. (A) qRT-PCR analysis of mRNA levels of key EMT-related genes in vector and PKM2 groups in vitro. (B,C) Western blotting analysis of protein levels of EMT marker proteins in footpad tumors sh-PKM2 and sh-NC groups in vivo. (D) Typical micrographs of IHC-stained in footpad tumors sh-PKM2 and sh-NC groups in vivo. *P < 0.05, **P < 0.01, ***P < 0.001

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