myoepithelial carcinoma. (a) Spindle cell proliferation surrounding epithelial lumina, H&E × 400. (b) Higher power view showing pleomorphic spindle cells with eosinoplilic and clear cytoplasm surrounding an epithelial lined space, H&E × 400. (c) Another area showing pleomorphic spindle and ovoid cells with eosinophilic cytoplasm arranged in fascicles; cells have high mitotic activity, H&E × 400. (d) Pleomorphic spindle and ovoid cells with clear cytoplasm arranged in wavy fascicles, H&E × 400. (e) s100 p IHC staining of the myoepithelial cells around the epithelial lumina and the neoplastic spindle cells × DAB, Hx, ×10. (f) Higher magnification of "fig 4e" showing staining of almost all the cells for s100 p IHC, DAB, Hx, × 400. (g) CD10 IHC, DAB, Hx, × 400. see additional files 9, 10, 11, 1213, 14, 15 for higher resolution images.