The study presents a unique case of Adamantinoma-like Ewing Sarcoma (ALES) in the pancreatic tail, an atypical location for this rare subtype of Ewing sarcoma. A 43-year-old male patient with epigastric pain underwent surgery for a suspected pancreatic tumor, revealing infiltrative growth involving both the pancreatic tail and adrenal gland. Microscopic analysis demonstrated small round blue cell nests with epithelial differentiation, resembling adamantinoma. Immunohistochemistry confirmed positivity for cytokeratins, P40, CK5/6, CD99, and NKX2.2, along with variable FLI1 expression. Fluorescence in situ hybridization confirmed the EWSR1-FLI1 gene fusion. The case highlights the diagnostic complexities when ALES occurs in uncommon sites and contributes to understanding this unique subtype of Ewing sarcoma.
Featured Article of the Month
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Primary adenocarcinoma of the spermatic cord: a case report and review of the literature
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Anlotinib treatment for rapidly progressing pediatric embryonal rhabdomyosarcoma in the maxillary gingiva: a case report
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ITGA5 is associated with prognosis marker and immunosuppression in head and neck squamous cell carcinoma
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Spitz melanoma with MAP3K8::ABLIM1 rearrangement: a case report with review of the literature
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Antinuclear antibodies and their detection methods in diagnosis of connective tissue diseases: a journey revisited
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The value of CDX2 and cytokeratins 7 and 20 expression in differentiating colorectal adenocarcinomas from extraintestinal gastrointestinal adenocarcinomas: cytokeratin 7-/20+ phenotype is more specific than CDX2 antibody
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Quantitative comparison of immunohistochemical staining measured by digital image analysis versus pathologist visual scoring
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An unusual case of Acanthamoeba Polyphaga and Pseudomonas Aeruginosa keratitis
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p16 as a diagnostic marker of cervical neoplasia: a tissue microarray study of 796 archival specimens
Call for Papers: Pediatric Pathology Cancers
We warmly welcome submissions to our Collection on Pediatric Pathology Cancers, Guest Edited by Shamlal Mangray. This Collection invites original research articles and reviews aiming to enhance our understanding of childhood cancers.
Image credit: © Shamlal Mangray
Read MoreCall for Papers: Precision Pathology: A New Frontier for Diagnostic Pathology
This collection of articles aims to explore the exciting developments and opportunities that precision pathology brings to the forefront of healthcare. It will delve into topics such as genomics, proteomics, and computational-enabled precise pathology diagnostics, which are revolutionizing the way we analyse and interpret pathology specimens and data.
Image credit: © LALAKA / stock.adobe.com
Featured Image of the Month
Global Advances in AI: Innovations in Digital Pathology and Radiology 2022
Kameda Medical Center (Japan), Nagasaki University (Japan) and The Ohio State University (USA) are teaming up to present a virtual joint conference on Global Advances in AI: Innovations in Digital Pathology and Radiology 2022. International speakers will share up-to-date information on AI development in pathology and radiology.
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Artificial Intelligence in Cancer Imaging and Diagnosis
New tools and technologies such as computational and digital pathology, molecular diagnostics and artificial intelligence (AI) are making their way into advanced clinical diagnostics, providing some unique opportunities to incorporate these tools into the evolving health care landscape. We're proud to present a cross journal series with articles that would give the viewer a perspective of the current trends and future prospects of AI primarily in clinical diagnostics. Read here.
Annual Journal Metrics
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Citation Impact 2023
Journal Impact Factor: 2.4
5-year Journal Impact Factor: 2.6
Source Normalized Impact per Paper (SNIP): 1.073
SCImago Journal Rank (SJR): 0.697Speed 2023
Submission to first editorial decision (median days): 24
Submission to acceptance (median days): 119Usage 2023
Downloads: 1,109,481
Altmetric mentions: 429