The study presents a unique case of Adamantinoma-like Ewing Sarcoma (ALES) in the pancreatic tail, an atypical location for this rare subtype of Ewing sarcoma. A 43-year-old male patient with epigastric pain underwent surgery for a suspected pancreatic tumor, revealing infiltrative growth involving both the pancreatic tail and adrenal gland. Microscopic analysis demonstrated small round blue cell nests with epithelial differentiation, resembling adamantinoma. Immunohistochemistry confirmed positivity for cytokeratins, P40, CK5/6, CD99, and NKX2.2, along with variable FLI1 expression. Fluorescence in situ hybridization confirmed the EWSR1-FLI1 gene fusion. The case highlights the diagnostic complexities when ALES occurs in uncommon sites and contributes to understanding this unique subtype of Ewing sarcoma.
Featured Article of the Month
Featured Image of the Month
Kameda Medical Center (Japan), Nagasaki University (Japan) and The Ohio State University (USA) are teaming up to present a virtual joint conference on Global Advances in AI: Innovations in Digital Pathology and Radiology 2022. International speakers will share up-to-date information on AI development in pathology and radiology.
New tools and technologies such as computational and digital pathology, molecular diagnostics and artificial intelligence (AI) are making their way into advanced clinical diagnostics, providing some unique opportunities to incorporate these tools into the evolving health care landscape. We're proud to present a cross journal series with articles that would give the viewer a perspective of the current trends and future prospects of AI primarily in clinical diagnostics. Read here.
Dr Anil Parwani, Editor-in-Chief
"Diagnostic Pathology has emerged as a premier journal that aims to publish cutting edge articles focused on diagnostic pathology with an emphasis on novel morphological and molecular findings that make an impact on diagnosis of neoplastic and non-neoplastic diseases. The goal of the editorial board and our team is to highlight the cross-roads of diagnostic pathology and new tools and technologies that are exciting, challenging and making an impact on the practice of pathology. We will continue to bring updates in the field of diagnostic pathology by way of novel and interesting case reports, research and original articles and a series of key review articles by experts in the field that will emphasize the new developments which are disease-specific and highlight contemporary and novel technologies that are changing the practice of diagnostic pathology. This is an exciting time in pathology as we are confronted with a new frontier of science and technology which continues to evolve and accelerate the discipline of diagnostic pathology and we wish to take our readers with us on this exciting journey. We want to collaborate with our reviewers and our readers to make Diagnostic Pathology a premier and trusted source of new and exciting developments in the field of diagnostic pathology."
Dr Anil Parwani, Ohio State University
Annual Journal Metrics
2022 Citation Impact
2.6 - 2-year Impact Factor
2.7 - 5-year Impact Factor
1.096 - SNIP (Source Normalized Impact per Paper)
0.677 - SJR (SCImago Journal Rank)
67 days submission to first editorial decision for all manuscripts (Median)
173 days submission to accept (Median)
735 Altmetric mentions