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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. Nonsense mutation or inactivation of SMARCA4 (BRG1) is associated with a monomorphic undifferentiated histological appearance in tumors at different sites. The association between SMARCA4 alteration and undiff...

    Authors: Huanli Duan, Wei Gao, Leiming Wang, Feng Cao and Lianghong Teng

    Citation: Diagnostic Pathology 2021 16:30

    Content type: Case Report

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  2. Primary hepatic mucoepidermoid carcinoma (HMEC) is extremely rare and the molecular etiology is still unknown. The CRTC1-MAML2 fusion gene was previously detected in a primary HMEC, which is often associated with...

    Authors: Ping Hou, Xiaoyan Su, Wei Cao, Liping Xu, Rongguiyi Zhang, Zhihao Huang, Jiakun Wang, Lixiang Li, Linquan Wu and Wenjun Liao

    Citation: Diagnostic Pathology 2021 16:29

    Content type: Research

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  3. This study aimed to investigate the association between clinicopathologic factors, mesothelin, and cancer antigen (CA) 125 in endometrial carcinoma.

    Authors: Soichiro Kakimoto, Morikazu Miyamoto, Takahiro Einama, Yasuhiro Takihata, Hiroko Matsuura, Hideki Iwahashi, Hiroki Ishibashi, Takahiro Sakamoto, Taira Hada, Jin Suminokura, Tsubasa Ito, Rie Suzuki, Ayako Suzuki and Masashi Takano

    Citation: Diagnostic Pathology 2021 16:28

    Content type: Research

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  4. TWIST1 and CD105, which contribute to tumor malignancy, are overexpressed in cancers. Accordingly, TWIST1 enhances epithelial-to-mesenchymal transition (EMT) and promotes the formation of cancer stem cells (CS...

    Authors: Fahimeh Fattahi, Leili Saeednejad Zanjani, Somayeh Vafaei, Zohreh Habibi Shams, Jafar Kiani, Marzieh Naseri, Elmira Gheytanchi and Zahra Madjd

    Citation: Diagnostic Pathology 2021 16:26

    Content type: Research

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  5. Fine-needle aspiration (FNA) is a frequently utilized method for the diagnosis of thyroid nodules. Although the technique has clear advantages, the injury caused by the aspiration needle can induce various his...

    Authors: Woo Sung Moon, Myoung Jae Kang, Hyun Jo Youn and Kyoung Min Kim

    Citation: Diagnostic Pathology 2021 16:25

    Content type: Case Report

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  6. The role of Artificial intelligence (AI) which is defined as the ability of computers to perform tasks that normally require human intelligence is constantly expanding. Medicine was slow to embrace AI. However...

    Authors: Zubair Ahmad, Shabina Rahim, Maha Zubair and Jamshid Abdul-Ghafar

    Citation: Diagnostic Pathology 2021 16:24

    Content type: Review

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  7. Kaposiform Hemangioendothelioma (KHE) is a rare vascular tumor of intermediate malignant potential which shows locally aggressive growth but only rarely metastasizes. It is mostly considered to be a tumor of p...

    Authors: Qurratulain Chundriger, Muhammad Usman Tariq, Jamshid Abdul-Ghafar, Arsalan Ahmed and Nasir Ud Din

    Citation: Diagnostic Pathology 2021 16:23

    Content type: Research

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  8. Sialadenoma papilliferum (SP) is an extremely rare benign neoplasm of salivary glands. To explore and define the clinicopathological features of SP, we retrospectively analyzed 89 cases previously reported and...

    Authors: Shuai Chen, Jie Peng, Chuantao Yuan, Lin Sun, Renya Zhang and Yan Sun

    Citation: Diagnostic Pathology 2021 16:22

    Content type: Research

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  9. In lung cancer management, differential diagnosis between multiple primary lung cancer (MPLC) and intrapulmonary metastasis (IMP) is a critical point that is of direct therapeutic and clinical importance. Howe...

    Authors: Changjiang Liu, Chengang Liu, Xiao Zou, Lin Shao, Ying Sun and Yang Guo

    Citation: Diagnostic Pathology 2021 16:21

    Content type: Case Report

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  10. Making the distinction between primary mucinous and metastatic ovarian tumors is often difficult, especially in tumors with a primary source from the gastrointestinal tract, pancreas and biliary tree. The aim ...

    Authors: Pavel Dundr, Naveena Singh, Barbora Nožičková, Kristýna Němejcová, Michaela Bártů and Ivana Stružinská

    Citation: Diagnostic Pathology 2021 16:20

    Content type: Review

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  11. Immunohistochemistry (IHC) remains the gold standard for the diagnosis of pathological diseases. This technique has been supporting pathologists in making precise decisions regarding differential diagnosis and...

    Authors: Yosep Chong, Nishant Thakur, Ji Young Lee, Gyoyeon Hwang, Myungjin Choi, Yejin Kim, Hwanjo Yu and Mee Yon Cho

    Citation: Diagnostic Pathology 2021 16:19

    Content type: Research

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  12. Metastases are common in non-cirrhotic livers but are considered unlikely in the setting of cirrhosis. However, the degree of fibrosis in cirrhosis may vary; thus metastases may still access the liver vasculat...

    Authors: Zaid Mahdi, Mark G. Ettel, Raul S. Gonzalez, John Hart, Lindsay Alpert, Jiayun Fang, Natalia Liu, Suntrea T. Hammer, Nicole Panarelli, Jerome Cheng, Joel K. Greenson, Paul E. Swanson and Maria Westerhoff

    Citation: Diagnostic Pathology 2021 16:18

    Content type: Research

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  13. Patients with head and neck squamous cell carcinoma (HNSCC) can develop lung squamous cell carcinoma (LuSCC), which could be the second primary tumor or HNSCC metastasis. Morphologically it is difficult to dis...

    Authors: Maja Šutić, Jurica Baranašić, Lana Kovač Bilić, Mario Bilić, Antonija Jakovčević, Luka Brčić, Sven Seiwerth, Marko Jakopović, Miroslav Samaržija, Ulrich Zechner and Jelena Knežević

    Citation: Diagnostic Pathology 2021 16:17

    Content type: Short report

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  14. To date, very few studies on clinical-histopathological correlations of cutaneous disorders associated with COVID-19 have been conducted.

    Authors: Angela Patrì, Maria Vargas, Pasquale Buonanno, Maria Carmela Annunziata, Daniela Russo, Stefania Staibano, Giuseppe Servillo and Gabriella Fabbrocini

    Citation: Diagnostic Pathology 2021 16:16

    Content type: Case Report

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  15. A 52-year-old woman presented with shortness of breath and cough. An endobronchial sialolipoma was found at the left entrance of the main bronchus. Sialolipoma is an exceedingly rare type of lipoma reported of...

    Authors: Severino Rey Nodar, Verónica García Yllán, Nohelia Rojas Ferrer, Onay Solis and Hugo D. Boccara

    Citation: Diagnostic Pathology 2021 16:15

    Content type: Case Report

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  16. Succinate dehydrogenase deficient gastrointestinal stromal tumors (SDH-deficient GISTs), which lack KIT or PDGFRA mutations demonstrate unique clinical and pathological features, and they respond poorly to sta...

    Authors: Bei-Bei Lv, Jia-Mei Li, Zhi-Gang Yao, Xian-Kui Cheng, Fu-Xin Ren, Wen-Jing Su, Ye-Jun Qin, Zhou Wang and Zhi-xin Cao

    Citation: Diagnostic Pathology 2021 16:14

    Content type: Case Report

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  17. The consistency of pathologists in the diagnosis of cervical intraepithelial neoplasia (CINs) is not ideal, especially between low- and high-grade squamous intraepithelial lesions (LSIL and HSIL). This study w...

    Authors: Chang Hui, Huimin Bai, Jun Liu, Xuerong Lu, Shuzhen Wang, Zhenyu Zhang, Mulan Jin, Yue Wang and Yuzhen Liu

    Citation: Diagnostic Pathology 2021 16:13

    Content type: Research

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  18. Ovarian clear cell carcinoma (OCCC) is the second subtype of ovarian epithelial carcinoma reported to be closely related to Lynch syndrome (LS). ARID1A mutation is an important pathogenetic mechanism in OCCC t...

    Authors: Huijuan Ge, Yaoxin Xiao, Guangqi Qin, Yanzi Gu, Xu Cai, Wenhua Jiang, Xiaoyu Tu, Wentao Yang and Rui Bi

    Citation: Diagnostic Pathology 2021 16:12

    Content type: Research

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  19. The majority of gastrointestinal tumors are adenocarcinomas. Rarely, there are other types of tumors, such as acinar cell carcinoma, and these are often called pancreatic-type acinar cell carcinomas. Among the...

    Authors: Yuka Ooe, Kishichiro Watanabe, Isaya Hashimoto, Satoshi Takenaka, Toshihiko Ojima, Seiichi Yamamoto and Hisatake Fujii

    Citation: Diagnostic Pathology 2021 16:11

    Content type: Case Report

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  20. Glutathione S-transferase mu 3 (GSTM3) plays a crucial role in tumor progression in various cancers. However, the relationship between GSTM3 expression and the clinical prognosis of esophageal squamous cell ca...

    Authors: Fu Yang, Jing Wen, Kongjia Luo and Jianhua Fu

    Citation: Diagnostic Pathology 2021 16:10

    Content type: Research

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  21. To explore the clinical characteristics and placental pathological changes of pregnant women with 2019 novel coronavirus (CoV) disease (COVID-19) in the third trimester, and to assess the possibility of vertic...

    Authors: Likun Gao, Jiacai Ren, Li Xu, Xiaokang Ke, Lin Xiong, Xiaoli Tian, Cuifang Fan, Honglin Yan and Jingping Yuan

    Citation: Diagnostic Pathology 2021 16:8

    Content type: Case Report

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  22. Histiocytic sarcoma (HS) is a rare neoplasm showing morphological and immunophenotypic features of mature tissue histiocytes. We report a patient with nodal HS exhibiting prominent reactive eosinophilic infilt...

    Authors: Rintaro Ohe, Takanobu Kabasawa, Aya Utsunomiya, Yuka Urano, Takumi Kitaoka, Kazushi Suzuki, Naing Ye Aung, Ichiro Kawamura, Katsushi Tajima, Tomoharu Ishiyama and Mitsunori Yamakawa

    Citation: Diagnostic Pathology 2021 16:6

    Content type: Case Report

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  23. Gastric cancer (GCa) is one of the six major malignancies in the world with low survival rate. Although there are advances in therapeutic approaches, the prognosis of patients with GCa remains not optimistic. ...

    Authors: Zhong Zheng, Jun Li, Junyan An, Yikuan Feng and Lirong Wang

    Citation: Diagnostic Pathology 2021 16:5

    Content type: Research

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  24. IL4Rα and IL13Rα1 are constituents of the type II IL4 receptor. Recently, IL4Rα and IL13Rα1 were reported to have roles in cancer progression and suggested as potential prognostic markers. However, studies on ...

    Authors: Kyoung Min Kim, Usama Khamis Hussein, See-Hyoung Park, Young Jae Moon, Zhongkai Zhang, Asmaa Gamal Ahmed, Ae-Ri Ahn, Ho Sung Park, Jung Ryul Kim and Kyu Yun Jang

    Citation: Diagnostic Pathology 2021 16:2

    Content type: Research

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  25. Anaplastic large cell lymphoma (ALCL) with uniform CD56 expression is a rare condition, that has been described in limited literature, and its clinicopathological features have not yet been well illustrated. T...

    Authors: Bao-Hua Yu, Yan Zhang, Tian Xue, Ruo-Hong Shui, Hong-Fen Lu, Xiao-Yan Zhou, Xiong-Zeng Zhu and Xiao-Qiu Li

    Citation: Diagnostic Pathology 2021 16:1

    Content type: Research

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  26. Identification of somatic mutations in key oncogenes in melanoma is important to lead the effective and efficient use of personalized anticancer treatment. Conventional methods focus on few genes per run and, ...

    Authors: Irene Vanni, Milena Casula, Lorenza Pastorino, Antonella Manca, Bruna Dalmasso, Virginia Andreotti, Marina Pisano, Maria Colombino, Ulrich Pfeffer, Enrica Teresa Tanda, Carla Rozzo, Panagiotis Paliogiannis, Antonio Cossu, Paola Ghiorzo and Giuseppe Palmieri

    Citation: Diagnostic Pathology 2020 15:143

    Content type: Research

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  27. The involvement of circular RNAs (circRNAs) in chemoresistance of tumors has been identified. Herein, this study aims to investigate the role and the underlying mechanism of circ_0003998 in doxorubicin (DOX) r...

    Authors: Xiaomin Li, Jiefeng He, Xiaojing Ren, Haichao Zhao and Haoliang Zhao

    Citation: Diagnostic Pathology 2020 15:141

    Content type: Research

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  28. Pancreatic Solid Pseudopapillary Neoplasms (SPNs) are rare low-grade malignant tumors with a marked preponderance for young females. Objective was to describe the morphology, differential diagnosis, and progno...

    Authors: Nasir Ud Din, Shabina Rahim, Jamshid Abdul-Ghafar, Arsalan Ahmed and Zubair Ahmad

    Citation: Diagnostic Pathology 2020 15:139

    Content type: Research

    Published on:

  29. High grade basal-like breast carcinomas are triple negative, express basal cytokeratins, and are known for the overall poor prognosis and aggressive behavior. HPV related multiphenotypic sino-nasal carcinoma h...

    Authors: Diana M. Oramas, Diana Bell and Lavinia P. Middleton

    Citation: Diagnostic Pathology 2020 15:137

    Content type: Case Report

    Published on:

  30. Karyopherin α2 (KPNA2), a member of the karyopherin α family, has been studied in several cancers but has not yet been substantially investigated in malignant bone tumors. The purpose of the current study was ...

    Authors: Lucen Jiang, Jianghuan Liu, Qingzhu Wei and Yiyang Wang

    Citation: Diagnostic Pathology 2020 15:135

    Content type: Research

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  31. Pulmonary NUT carcinoma is rare, but lethal, thus, must not be overlooked. The definitive diagnosis is made by a NUT monoclonal antibody or gene analysis, but these are not always routinely available. Therefor...

    Authors: Satoe Numakura, Koji Saito, Noriko Motoi, Taisuke Mori, Yuichi Saito, Fumi Yokote, Yasuyuki Kanamoto, Momoko Asami, Takashi Sakai, Yoshikane Yamauchi, Yukinori Sakao, Hiroshi Uozaki and Masafumi Kawamura

    Citation: Diagnostic Pathology 2020 15:134

    Content type: Case Report

    Published on:

  32. Lung cancer (LC) is a malignant tumor originating in the bronchial mucosa or gland of the lung. Circular RNAs (circRNAs) are proved to be key regulators of tumor progression. However, the regulatory effect of ...

    Authors: Koudong Zhang, Hang Hu, Juan Xu, Limin Qiu, Haitao Chen, Xingzhi Jiang and Yongqian Jiang

    Citation: Diagnostic Pathology 2020 15:133

    Content type: Research

    Published on:

  33. Spitzoid melanocytic lesions represent a heterogeneous group of proliferations with ambiguous and overlapping terminology. The exact distinction of a Spitz nevus from a Spitzoid melanoma can be very difficult ...

    Authors: Jiri Vachtenheim Jr, Roman Kodet, Ondrej Fischer, Vitezslav Kolek, Zuzana Strizova, Andrej Ozaniak, Jan Simonek, Alan Stolz, Jiri Pozniak, Jan Kolarik, Monika Svorcova, Jiri Vachtenheim and Robert Lischke

    Citation: Diagnostic Pathology 2020 15:132

    Content type: Case Report

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  34. Gastric adenocarcinoma of the fundic gland type (GA-FG) has been added to the 2019 edition of the World Health Organization’s list of digestive system-associated cancers. This lesion differentiates toward the ...

    Authors: Chengfang Li, Xinglong Wu, Shuang Yang, Xiaorong Yang, Jin Yao and Hong Zheng

    Citation: Diagnostic Pathology 2020 15:131

    Content type: Research

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  35. The conventional method for the diagnosis of malaria parasites is the microscopic examination of stained blood films, which is time consuming and requires expertise. We introduce computer-based image segmentat...

    Authors: Syed Saiden Abbas and Tjeerd M. H. Dijkstra

    Citation: Diagnostic Pathology 2020 15:130

    Content type: Research

    Published on:

  36. Histologic features of idiopathic non-cirrhotic portal hypertension (INCPH) may overlap with those without INCPH. Recently, these features have been recognized as part of the larger spectrum of porto-sinusoida...

    Authors: Michel Kmeid, Chunlai Zuo, Stephen M. Lagana, Won-Tak Choi, Jingmei Lin, Zhaohai Yang, Xiuli Liu, Maria Westerhoff, M. Isabel Fiel, Kajsa Affolter, Eun-Young K. Choi and Hwajeong Lee

    Citation: Diagnostic Pathology 2020 15:129

    Content type: Research

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  37. Colorectal T/natural killer (NK)-cell lymphomas (TNKCL) are very rare. Endoscopic and clinicopathological characteristics of colorectal TNKCL have not been clearly demonstrated. In this study, we demonstrated ...

    Authors: Hideki Ishibashi, Satoshi Nimura, Fumihito Hirai, Naohiko Harada, Hiromi Iwasaki, Sigeto Kawauchi, Yumi Oshiro, Atsuji Matsuyama, Shotaro Nakamura, Yasushi Takamatsu, Hirotoshi Yonemasu, Taturo Shimokama and Morishige Takeshita

    Citation: Diagnostic Pathology 2020 15:128

    Content type: Research

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  38. Histologic distinction between well differentiated hepatocellular carcinoma (HCC) and benign hepatocellular mass lesions is a known challenge. Existing biomarkers are of limited diagnostic value. Our previous ...

    Authors: Yuan Li, Fangfang Liu, Wendi Zhou, Sharon Zhang, Peiguo Chu, Fan Lin and Hanlin L. Wang

    Citation: Diagnostic Pathology 2020 15:127

    Content type: Research

    Published on:

  39. Esophageal squamous cell carcinoma (ESCC) still remains intractable disease with few therapeutic options. Programmed death-ligand 1 (PD-L1), which is essential for immune evasion, is involved in the pathogenes...

    Authors: Hong Kyu Lee, Mi Jung Kwon, Yong Joon Ra, Hee Sung Lee, Hyoung Soo Kim, Eun Sook Nam, Seong Jin Cho, Hye-Rim Park, Soo Kee Min, Jinwon Seo, Ji-Young Choe, Kyueng-Whan Min and So Young Kang

    Citation: Diagnostic Pathology 2020 15:126

    Content type: Research

    Published on:

  40. Epstein–Barr virus (EBV) is associated with the pathogenesis of a variety of malignancies, most notably lymphomas. Especially in the background of immunodeficiency, such as primary immunodeficiency disorder (P...

    Authors: Yusuke Kajimoto, Yasuhiro Terasaki, Mika Terasaki, Shinobu Kunugi, Yugo Okabe, Satoshi Wakita, Koiti Inokuchi and Akira Shimizu

    Citation: Diagnostic Pathology 2020 15:125

    Content type: Case Report

    Published on:

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