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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. Cutaneous T-cell lymphomas (CTCL) are a heterogeneous group of extranodal non-Hodgkin lymphomas for which diagnosis can be challenging given the potential for overlap with inflammatory dermatoses. Current diag...

    Authors: Rebecca Rojansky, Sebastian Fernandez-Pol, Erica Wang, Kerri E. Rieger, Roberto A. Novoa, James L. Zehnder, Christian A. Kunder, Youn H. Kim, Michael S. Khodadoust and Ryanne A. Brown

    Citation: Diagnostic Pathology 2020 15:122

    Content type: Case Report

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  2. Cytokeratin-positive interstitial reticulum cells (CIRCs), which are a subgroup of fibroblastic reticular cells (FRCs), are known to be present in the lymph nodes. There have been only a few cases of tumors de...

    Authors: Sachiko Kaji, Nobuyuki Hiruta, Daisuke Sasai, Makoto Nagashima, Rintaro Ohe and Mitsunori Yamakawa

    Citation: Diagnostic Pathology 2020 15:121

    Content type: Case Report

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  3. Hepatic epithelioid hemangioendothelioma is an extremely rare malignant vascular tumor which is often multifocal and, in many cases, discovered incidentally. Here, we describe the clinicopathological features ...

    Authors: Nasir Ud Din, Shabina Rahim, Tamana Asghari, Jamshid Abdul-Ghafar and Zubair Ahmad

    Citation: Diagnostic Pathology 2020 15:120

    Content type: Research

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  4. Uterine adenosarcoma, a rare uterine tumor subtype, is a biphasic tumor consisting of epithelial and mesenchymal elements. To date, there is no research comparing the histopathological features and immunohisto...

    Authors: Makiko Omi, Akiko Tonooka, Tomohiro Chiba, Yuji Tanaka, Atsushi Fusegi, Yoichi Aoki, Hidetaka Nomura, Hiroyuki Kanao and Yutaka Takazawa

    Citation: Diagnostic Pathology 2020 15:119

    Content type: Research

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  5. Carcinosarcoma is a rare neoplasm with a poor prognosis that is most often discovered at an advanced stage; a gastric carcinosarcoma is even rarer than carcinosarcomas originating in other organs, such as the ...

    Authors: Akihiro Shioya, Nozomu Kurose, Kenichi Mizutani, Motona Kumagai, Ken Kawaura, Naohiko Nakamura, Takeo Kosaka, Nozomu Motono, Hidetaka Uramoto and Sohsuke Yamada

    Citation: Diagnostic Pathology 2020 15:118

    Content type: Case Report

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  6. Primary cardiac lymphomas are extremely rare entities (< 2% of cardiac tumours) and the most frequent histologic type is diffuse large B-cell lymphoma (DLBCL). Fibrin-associated DLBCL (FA-DLBCL) is a very unus...

    Authors: Esther Moreno Moreno, Ana Ferrer-Gómez, Héctor Pian Arias, Irene García García and Mónica García-Cosío

    Citation: Diagnostic Pathology 2020 15:117

    Content type: Case Report

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  7. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Danielle J. Fassler, Shahira Abousamra, Rajarsi Gupta, Chao Chen, Maozheng Zhao, David Paredes, Syeda Areeha Batool, Beatrice S. Knudsen, Luisa Escobar-Hoyos, Kenneth R. Shroyer, Dimitris Samaras, Tahsin Kurc and Joel Saltz

    Citation: Diagnostic Pathology 2020 15:116

    Content type: Publisher Correction

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    The original article was published in Diagnostic Pathology 2020 15:100

  8. Lymphoepithelioma-like carcinoma is a rare distinctive variant of liver cancer with unique epidemiological and pathological characteristics, characterized by dense lymphocyte infiltration. It can be divided in...

    Authors: Kai Zhang, Changcheng Tao, Zonggui Tao, Fan Wu, Songlin An, Jianxiong Wu and Weiqi Rong

    Citation: Diagnostic Pathology 2020 15:115

    Content type: Case Report

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  9. While ETV6- NTRK3 fusion is common in infantile fibrosarcoma, NTRK1/3 fusion in pediatric tumors is scarce and, consequently, not well known. Herein, we evaluated for the presence of NTRK1/3 fusion in pediatric m...

    Authors: Jeongwan Kang, Jin Woo Park, Jae-Kyung Won, Jeong Mo Bae, Jaemoon Koh, Jeemin Yim, Hongseok Yun, Seung-Ki Kim, Jung Yoon Choi, Hyoung Jin Kang, Woo Sun Kim, Joo Heon Shin and Sung-Hye Park

    Citation: Diagnostic Pathology 2020 15:114

    Content type: Research

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  10. Fine needle aspiration cytology (FNAC) with rapid on-site evaluation has a great potential for the diagnosis of fungal lesions and other opportunistic infections. Fungal infections have been in increasing tren...

    Authors: Santosh Tummidi, Bitan Naik, Arundhathi Shankaralingappa, Pavithra Balakrishna, Arati Ankushrao Bhadada and Navya Kosaraju

    Citation: Diagnostic Pathology 2020 15:113

    Content type: Case Report

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  11. Peripheral blood smears are performed to evaluate a variety of hematologic and non-hematologic disorders. At the authors’ institutions, clinician requests for pathologist-performed blood smear reviews have inc...

    Authors: Amy K. Beckman, Valerie L. Ng, David L. Jaye, Manila Gaddh, Sarah A. Williams, Sophia L. Yohe, Lin Zhang and Michael A. Linden

    Citation: Diagnostic Pathology 2020 15:112

    Content type: Research

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  12. Crawling-type adenocarcinoma (CRA) is an important gastric cancer (GC) subtype that exhibits a specific histological pattern and has characteristic clinicopathological findings. Despite its characteristic hist...

    Authors: Yasuko Fujita, Noriyuki Uesugi, Ryo Sugimoto, Makoto Eizuka, Yosuke Toya, Risaburo Akasaka, Takayuki Matsumoto and Tamotsu Sugai

    Citation: Diagnostic Pathology 2020 15:111

    Content type: Research

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  13. Uterine tumors resembling ovarian sex-cord tumors (UTROSCTs) are rare mesenchymal neoplasms predominantly arising in perimenopausal and postmenopausal women. UTROSCTs with growth regulation by estrogen in brea...

    Authors: Bin Chang, Qianming Bai, Lin Liang, Huijuan Ge and Qianlan Yao

    Citation: Diagnostic Pathology 2020 15:110

    Content type: Case Report

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  14. Kang and colleagues evaluated on a case series of 1848 breast cancer (BC) patients operated for a first primary ER positive HER2 negative BC if Ki67 expression is a significant prognostic factor only when PgR ...

    Authors: Roberta Maltoni, Michela Palleschi, Sara Ravaioli, Maria Maddalena Tumedei, Mattia Altini and Sara Bravaccini

    Citation: Diagnostic Pathology 2020 15:109

    Content type: Commentary

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  15. Chromogranin A (CgA), synaptophysin (Syn) and the Ki-67 index play significant roles in diagnosis or the evaluation of the proliferative activity of gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs). ...

    Authors: Huiying Shi, Chen Jiang, Qin Zhang, Cuihua Qi, Hailing Yao and Rong Lin

    Citation: Diagnostic Pathology 2020 15:108

    Content type: Research

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  16. Intestinal-type adenocarcinoma is widely detected in the gastrointestinal tract, head and neck, lower respiratory and urinary systems. Determining the nature (monoclonal or multicentric) of the intestinal aden...

    Authors: Mikiko Matsuo, Yuichiro Hatano, Yuko Imaizumi, Takahiro Kuroda, Toshinori Arai, Hiroyuki Tomita, Nobuhisa Matsuhashi, Kazuhiro Yoshida and Akira Hara

    Citation: Diagnostic Pathology 2020 15:106

    Content type: Case Report

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  17. Pulmonary epithelial–myoepithelial carcinoma is a rare subtype of lung cancer. Because of its rarity, the molecular information on this carcinoma is insufficient.

    Authors: Naoki Yanagawa, Ayaka Sato, Masao Nishiya, Masamichi Suzuki, Ryo Sugimoto, Mitsumasa Osakabe, Noriyuki Uesugi, Hajime Saito and Tamotsu Sugai

    Citation: Diagnostic Pathology 2020 15:105

    Content type: Case Report

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  18. Squamous cell carcinomas and adenocarcinomas are the most common types of cervical cancer. Compared to squamous cell carcinomas, adenocarcinomas are more common in younger women and have a poorer prognosis. Ye...

    Authors: Hailing Li, Xiaotong Jing, Jie Yu, Jiannan Liu, Tingguo Zhang, Shiming Chen and Xiaofang Zhang

    Citation: Diagnostic Pathology 2020 15:104

    Content type: Research

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  19. The world is currently witnessing a major devastating pandemic of Coronavirus disease-2019 (COVID-19). This disease is caused by a novel coronavirus named Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-...

    Authors: Sambit K. Mohanty, Abhishek Satapathy, Machita M. Naidu, Sanjay Mukhopadhyay, Shivani Sharma, Lisa M. Barton, Edana Stroberg, Eric J. Duval, Dinesh Pradhan, Alexandar Tzankov and Anil V. Parwani

    Citation: Diagnostic Pathology 2020 15:103

    Content type: Review

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  20. Ductal carcinoma of the prostate is a histological subtype with a higher mortality than acinar adenocarcinoma. The number of cases is small and there are no treatment guidelines. We believe that this is the fi...

    Authors: Kota Umeda, Takeo Kosaka, Kohei Nakamura, Toshikazu Takeda, Shuji Mikami, Hiroshi Nishihara and Mototsugu Oya

    Citation: Diagnostic Pathology 2020 15:102

    Content type: Case Report

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  21. MicroRNAs (miRNAs) serve as novel promising biomarkers for the diagnosis and prognosis of many human diseases. This study investigated the diagnostic value of miR-186-5p for asymptomatic carotid artery stenosi...

    Authors: Weibo Lv, Tao Zhang, Hongwei Zhao, Shuang He, Bingwei Li, Yang Gao and Wenying Pan

    Citation: Diagnostic Pathology 2020 15:101

    Content type: Research

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  22. Multiplex immunohistochemistry (mIHC) permits the labeling of six or more distinct cell types within a single histologic tissue section. The classification of each cell type requires detection of uniquely colo...

    Authors: Danielle J. Fassler, Shahira Abousamra, Rajarsi Gupta, Chao Chen, Maozheng Zhao, David Paredes, Syeda Areeha Batool, Beatrice S. Knudsen, Luisa Escobar-Hoyos, Kenneth R. Shroyer, Dimitris Samaras, Tahsin Kurc and Joel Saltz

    Citation: Diagnostic Pathology 2020 15:100

    Content type: Research

    Published on:

    The Publisher Correction to this article has been published in Diagnostic Pathology 2020 15:116

  23. Molecular diagnostics can be decisive in the differential diagnosis between a somatic metastasis of type II testicular germ cell tumor (TGCT) or a second primary carcinoma. This is in line with recent recommen...

    Authors: Mariëtte E. G. Kranendonk, Wenzel M. Hackeng, G. Johan A. Offerhaus, Folkert H. M. Morsink, Geertruida N. Jonges, Gerard Groenewegen, Pieter-Jaap Krijtenburg, Heinz-Josef Klümpen, Wendy W. J. de Leng, Leendert H. J. Looijenga and Lodewijk A. A. Brosens

    Citation: Diagnostic Pathology 2020 15:99

    Content type: Case Report

    Published on:

  24. Fibro-adipose vascular anomaly (FAVA) is a new entity of vascular anomalies with somatic and mosaic gain-of-function mutations of the phosphatidylinositol-4, 5-bisphosphate 3-kinase catalytic subunit alpha (PIK3C...

    Authors: Yumiko Hori, Katsutoshi Hirose, Noriko Aramaki-Hattori, Sachi Suzuki, Robert Nakayama, Masanori Inoue, Takahiro Matsui, Masaharu Kohara, Satoru Toyosawa and Eiichi Morii

    Citation: Diagnostic Pathology 2020 15:98

    Content type: Case Report

    Published on:

  25. Malakoplakia is an uncommon, tumor-like inflammatory disease characterized by impaired histiocytes that are unable to completely digest phagocytized bacteria. The genitourinary tract is the most common site of...

    Authors: Michael Lee, Huaibin Mabel Ko, Anthony Rubino, Hwajeong Lee, Ryan Gill and Stephen M. Lagana

    Citation: Diagnostic Pathology 2020 15:97

    Content type: Research

    Published on:

  26. Several studies reported the dysregulation of miR-541 in the progression of some human malignancies. Osteosarcoma (OS) is one of the most common primary malignant bone tumors. This study aimed to assess the ex...

    Authors: Chunlei Liu and Xiuling Yi

    Citation: Diagnostic Pathology 2020 15:96

    Content type: Research

    Published on:

  27. Desmoplastic small round cell tumor (DSRCT) is a rare, aggressive neoplasm seen in children and young adults, usually manifested by involvement of abdominal serosa. Here, we present an unusual case of primary ...

    Authors: Dilek Ertoy Baydar, Ayse Armutlu, Oguz Aydin, Ayhan Dagdemir and Yarkin Kamil Yakupoglu

    Citation: Diagnostic Pathology 2020 15:95

    Content type: Case Report

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  28. Bladder cancer (BC) is a common and deadly disease. Over the past decade, a number of genetic alterations have been reported in BC. Bladder urothelium expresses abundant urea transporter UT-B encoded by Slc14a1 g...

    Authors: Zhongying Guo, Xiaobing Niu, Guangbo Fu, Baoxue Yang, Guangping Chen and Su’an Sun

    Citation: Diagnostic Pathology 2020 15:94

    Content type: Case Report

    Published on:

  29. Patients with 46, XY disorder of sex development (DSD) are predisposed to the development of gonadal tumors, particularly germ cell tumors and gonadoblastoma. However, to the best of our knowledge, there are n...

    Authors: Jiangying Zhao, Jiao Peng, Sisi He, Jia Yang and Xiaojun Pang

    Citation: Diagnostic Pathology 2020 15:93

    Content type: Case Report

    Published on:

  30. Mesonephric-like adenocarcinoma (M-LAC) is a rare, recently described tumor occurring in the uterine corpus and ovary, which shares the same morphological and immunohistochemical features with the more common ...

    Authors: Pavel Dundr, Mária Gregová, Kristýna Němejcová, Michaela Bártů, Nikola Hájková, Jan Hojný, Ivana Stružinská and Daniela Fischerová

    Citation: Diagnostic Pathology 2020 15:91

    Content type: Case Report

    Published on:

  31. Takotsubo cardiomyopathy is characterized by transient dysfunction of the medial to apical segment of the left ventricle. Recurrence within a few months or years has been reported and serious complications, in...

    Authors: Kenichi Mizutani, Akihiro Shioya, Yasuyo Hirose, Ryuhei Saito and Sohsuke Yamada

    Citation: Diagnostic Pathology 2020 15:90

    Content type: Case Report

    Published on:

  32. Anaplastic thyroid carcinoma (ATC) is a rare malignant tumor. In addition to the main ATC type with classical histopathological features, the other morphological types of ATC include paucicellular variant, ang...

    Authors: Jixuan Liu, Ni Cui, Wenjia Ding, Xinjie Dong, Xiaoshuai Chen, Jun Jiang and Yafang Liu

    Citation: Diagnostic Pathology 2020 15:89

    Content type: Case Report

    Published on:

  33. Malacoplakia is a rare chronic inflammatory disease. The name derives from the Greek “μαλακός” meaning “soft” and “πλάξ” meaning “plaque”, describing its usual macroscopic presentation as a friable yellow soft pl...

    Authors: Antonio d’Amati, Emilio Bellitti and Leonardo Resta

    Citation: Diagnostic Pathology 2020 15:88

    Content type: Case Report

    Published on:

  34. Identification of bladder layers is a necessary prerequisite to bladder cancer diagnosis and prognosis. We present a method of multi-class image segmentation, which recognizes urothelium, lamina propria, muscu...

    Authors: Muhammad Khalid Khan Niazi, Enes Yazgan, Thomas E. Tavolara, Wencheng Li, Cheryl T. Lee, Anil Parwani and Metin N. Gurcan

    Citation: Diagnostic Pathology 2020 15:87

    Content type: Research

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  35. Ovarian cancer is a spectrum of several histologically distinct tumor types that differ in etiology, response to therapy, and prognosis. In resource-limited settings, the diagnosis of ovarian cancer can be cha...

    Authors: Peter F. Rambau, Martin Köbel, Derek Tilley, Alex Mremi, Robert Lukande and William Muller

    Citation: Diagnostic Pathology 2020 15:86

    Content type: Research

    Published on:

  36. Immunohistochemistry (IHQ) is commonly used for the detection of mismatch repair proteins deficiency (MMRD). One very infrequent abnormal pattern of MMR protein expression is the loss of PMS2 and MSH6, with in...

    Authors: Esther Moreno, Juan M. Rosa-Rosa, Tamara Caniego-Casas, Ignacio Ruz-Caracuel, Cristian Perna, Carmen Guillén and José Palacios

    Citation: Diagnostic Pathology 2020 15:84

    Content type: Case Report

    Published on:

  37. E-cigarette and vaping use-associated acute lung injury (EVALI) has been recently recognized as a complication in individuals who use vaping devices. Another consideration is that EVALI may have an adverse inf...

    Authors: Bindu H. Akkanti, Rahat Hussain, Manish K. Patel, Jayeshkumar A. Patel, Kha Dinh, Bihong Zhao, Shaimaa Elzamly, Kevin Pelicon, Klemen Petek, Ismael A. Salas de Armas, Mehmet Akay, Biswajit Kar, Igor D. Gregoric and L. Maximilian Buja

    Citation: Diagnostic Pathology 2020 15:83

    Content type: Case Report

    Published on:

  38. Primary intestinal follicular lymphoma (PI-FL) is a rare and indolent lymphoma and is challenging for diagnosis with endoscopic biopsy specimens. Whole slide imaging (WSI) has been increasingly used for assist...

    Authors: Hsin-Ni Li, Ren Ching Wang, Jun-Peng Chen, Sheng-Tsung Chang and Shih-Sung Chuang

    Citation: Diagnostic Pathology 2020 15:82

    Content type: Research

    Published on:

  39. Pathologists frequently encounter neuroendocrine tumors (NETs) presenting as multiple liver masses in routine practice. Most often, these are well-differentiated tumors with characteristic histologic features....

    Authors: Elise R. Venable, Sarah E. Kerr, M. Beatriz S. Lopes, Karra A. Jones, Andrew M. Bellizzi, Taofic Mounajjed, Aditya Raghunathan, Oksana Hamidi, Thorvardur R. Halfdanarson, Mabel Ryder and Rondell P. Graham

    Citation: Diagnostic Pathology 2020 15:81

    Content type: Research

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  40. The mitotic count in breast carcinoma is an important prognostic marker. Unfortunately substantial inter- and intra-laboratory variation exists when pathologists manually count mitotic figures. Artificial inte...

    Authors: Liron Pantanowitz, Douglas Hartman, Yan Qi, Eun Yoon Cho, Beomseok Suh, Kyunghyun Paeng, Rajiv Dhir, Pamela Michelow, Scott Hazelhurst, Sang Yong Song and Soo Youn Cho

    Citation: Diagnostic Pathology 2020 15:80

    Content type: Research

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  41. Without early recognition and Kasai procedure, biliary atresia (BA) results in liver cirrhosis and leads to either transplantation or death at a young age. We aimed to characterize the liver histopathological ...

    Authors: Gunadi, Dian Nirmala Sirait, Leila Rakhma Budiarti, Vincentia Meta Widya Paramita, Aditya Rifqi Fauzi, Fiko Ryantono, Dwiki Afandy, Naomi Yoshuantari, Hanggoro Tri Rinonce and Akhmad Makhmudi

    Citation: Diagnostic Pathology 2020 15:79

    Content type: Research

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  42. The outbreak of a novel coronavirus since December 2019, became an emergency of major international concern. As of June 21, 2020, the SARS-CoV-2 pandemic has caused 8,769,844 confirmed infections with 463,745 ...

    Authors: Pan Zhai, Yanbing Ding and Yiming Li

    Citation: Diagnostic Pathology 2020 15:78

    Content type: Case Report

    Published on:

  43. This study evaluated the predictive power of Atyp.C (a parameter of UF-5000 flow cytometer) for patients with a suspected diagnosis of urothelial carcinoma.

    Authors: Chunyun Ren, Xing Wang, Chunwei Yang, Shengchao Li, Shuangchun Liu and Hongcui Cao

    Citation: Diagnostic Pathology 2020 15:77

    Content type: Research

    Published on:

  44. We examined the vascularity of mammary Paget disease histologically to confirm the increased blood flow observed previously by clinical imaging. The relationships among blood vessel density (BVD), histopatholo...

    Authors: Yuri Akishima-Fukasawa, Naoko Honma, Hideaki Ogata, Yoshikiyo Akasaka and Tetuo Mikami

    Citation: Diagnostic Pathology 2020 15:75

    Content type: Research

    Published on:

  45. Early diagnosis of asymptomatic carotid artery stenosis (ACAS) is important to prevent the incidence of cerebrovascular events. This study aimed to investigate the circulating expression of microRNA-92a (miR-9...

    Authors: Gang Chen, Jianwei Gao, Yuguo Sheng, Xinqiang Han, Xingang Ji, Mengpeng Zhao and Jian Wu

    Citation: Diagnostic Pathology 2020 15:74

    Content type: Research

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  46. In lung cancer patients infected with COVID-19, pathological features are not easy to distinguish. This report presents detailed histopathological findings in two non-neoplastic subjects whose out-of-hospital ...

    Authors: Roberto Scendoni, Francesca Marchesani, Nunzia Cannovo, Piergiorgio Fedeli and Mariano Cingolani

    Citation: Diagnostic Pathology 2020 15:73

    Content type: Commentary

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