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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. Mu heavy chain disease is a rare lymphoid neoplasm characterized by vacuolated bone marrow plasma cells and secretion of defective mu immunoglobulin heavy chains. The biological basis of mu heavy chain disease...

    Authors: Vandana Baloda, Sarah E. Wheeler, David L. Murray, Mindy C. Kohlhagen, Jeffrey A. VosUPMC, Svetlana A. Yatsenko, Mounzer E. Agha, Miroslav Djokic, Steven H. Swerdlow and Nathanael G. Bailey
    Citation: Diagnostic Pathology 2022 17:63
  2. We aimed to develop an artificial intelligence (AI)-assisted oral cytology method, similar to cervical cytology. We focused on the detection of cell nuclei because the ratio of cell nuclei to cytoplasm increas...

    Authors: Eiji Mitate, Kirin Inoue, Retsushi Sato, Youichi Shimomoto, Seigo Ohba, Kinuko Ogata, Tomoya Sakai, Jun Ohno, Ikuo Yamamoto and Izumi Asahina
    Citation: Diagnostic Pathology 2022 17:62
  3. Causative factors of breast cancer include infections, such as Epstein–Barr virus (EBV) infection. The aim of this study was to analyze the clinicopathological features of EBV-positive (IBC) and determine if E...

    Authors: Wei-tong Zhang, Gui-lu Zhu, Wu-qin Xu, Wei Zhang, Hui-zhen Wang, Ya-bing Wang and Yong-xiang Li
    Citation: Diagnostic Pathology 2022 17:61
  4. Contralateral neck lymph node metastasis is rare in primary breast cancer. Its clinical staging and treatment principles lack authoritative guidelines. A case of a 30-year-old breast cancer patient with contra...

    Authors: Xiaoxiao Zhong, Fengjiao Ding, Liyuan Qian, Wei Wu, Yanguang Wen and Boni Ding
    Citation: Diagnostic Pathology 2022 17:60
  5. Synovial sarcoma is an uncommon soft tissue tumor of soft tissue, characterized by a specific SS18 rearrangement. It generally manifests as a lesion composed of monomorphic spindle cells and sometimes shows va...

    Authors: Ying Chen, Ning Zhou, Deyu Guo, Xiaodong Wang, Xin He and Yujuan Xu
    Citation: Diagnostic Pathology 2022 17:59
  6. Plaque hardness in carotid artery stenosis correlates with cerebral infarction. This study aimed to quantitatively compare plaque hardness with histopathological findings and identify the pathological factors ...

    Authors: Daisuke Fukushima, Kosuke Kondo, Naoyuki Harada, Sayaka Terazono, Kei Uchino, Kazutoshi Shibuya and Nobuo Sugo
    Citation: Diagnostic Pathology 2022 17:58
  7. Vanishing bile duct syndrome (VBDS) is a rare but potentially severe acquired chronic cholestatic liver disease. Bile duct deficiency is a reduction of bile ducts in the liver, which can eventually lead to cho...

    Authors: Yuebo Jia, Lin Liu, Baocheng Deng, Yu Huang, Jiaqi Zhao and Guang Bai
    Citation: Diagnostic Pathology 2022 17:57
  8. The International System for Reporting Serous Fluid Cytopathology (TIS) was recently proposed. We retrospectively applied TIS recommendations for reporting the cytological diagnosis of serous effusions and rep...

    Authors: Yan-li Zhu, Wen-hao Ren, Qian Wang, Hai-zhu Jin, Yi-yi Guo and Dong-mei Lin
    Citation: Diagnostic Pathology 2022 17:56
  9. Rapid histologic diagnosis of frozen sections is essential for a variety of surgical procedures. Frozen sections however, require specialized lab equipment, are prone to freezing artifacts and are not applicab...

    Authors: Maja Carina Nackenhorst, Mohammad Kasiri, Bernd Gollackner and Heinz Regele
    Citation: Diagnostic Pathology 2022 17:55
  10. Former single center studies indicated that HER2 assessment with two primary tumor blocks (dual block HER2 assessment) could be an efficient and practical approach to overcome the adverse impact of heterogenei...

    Authors: Chen Xu, Miaomiao Sun, Mei Jin, Zengshan Li, Rong Qin, Guoping Ren, Wenyong Sun, Lirong Chen, Lijuan Luan, Yalan Liu, Dongxian Jiang, Lingli Chen, Rongkui Luo and Yingyong Hou
    Citation: Diagnostic Pathology 2022 17:54
  11. Primary intestinal T-cell lymphomas are uncommon malignancies that pose a diagnostic dilemma, because the clinical features and imaging findings commonly overlap with those encountered in inflammatory bowel di...

    Authors: Kashif Osmani, Eshana Shah, Bradley Drumheller, Shaun Webb, Manmeet Singh, Paul Rubinstein, John Patrick Galvin, Megan S. Lim and Carlos Murga-Zamalloa
    Citation: Diagnostic Pathology 2022 17:53
  12. Anaplastic lymphoma kinase rearrangement-associated renal cell carcinoma (ALK-RCC) is an extremely rare tumor and ALK-RCC that mimics mucinous tubular and spindle cell carcinoma (MTSCC) has been very reported ...

    Authors: Keita Kai, Shohei Tobu, Shinichi Kido, Shuji Mikami, Kengo Takeuchi, Akito Dobashi, Yuki Togashi, Mitsuru Noguchi and Shinichi Aishima
    Citation: Diagnostic Pathology 2022 17:52
  13. Malignant schwannoma is a malignant tumor of differentiation of Schwann cells or perineural cells.

    Authors: Imane Boujguenna, Hind Ousehal, Atmane Zaroual, Mohamed E. L. Bouderkaoui, Abdelaziz Raji, Chihab Bouyaali, Najat Cherif Idrissi El Ganouni, Anass Fakhri and Hanane Rais
    Citation: Diagnostic Pathology 2022 17:48
  14. We report a surgical case of urothelial carcinoma of the renal pelvis, resulting in diagnostic difficulties on cytological examination.

    Authors: Mao Takata, Motona Kumagai, Yumi Tsubata, Yoshiiku Okanemasa, Michiho Takenaka, Toshie Terauchi, Manabu Yamashita, Akihiro Shioya and Sohsuke Yamada
    Citation: Diagnostic Pathology 2022 17:47
  15. Neuroendocrine (NE) differentiation is widely studied in non-small cell lung carcinomas (NSCLC) however, its significance remains unclear in basaloid squamous cell carcinomas (B-SqCC). This study aims to asses...

    Authors: Kianoosh Keyhanian, William J. Phillips, Benjamin S. Yeung, Marcio Gomes, Bryan Lo and Harmanjatinder S. Sekhon
    Citation: Diagnostic Pathology 2022 17:46
  16. In breast cancer (BC) Ki-67 cut-off levels, counting methods and inter- and intraobserver variation are still unresolved. To reduce inter-laboratory differences, it has been proposed that cut-off levels for Ki...

    Authors: Anette H. Skjervold, Henrik Sahlin Pettersen, Marit Valla, Signe Opdahl and Anna M. Bofin
    Citation: Diagnostic Pathology 2022 17:45
  17. Ocular cystinosis is a rare autosomal recessive disorder characterized by intralysosomal cystine accumulation in renal, ophthalmic (cornea, conjunctiva), and other organ abnormalities. Patients with ocular cys...

    Authors: Latifa Chkioua, Yessine Amri, Chaima Saheli, Wassila Mili, Sameh Mabrouk, Imen Chabchoub, Hela Boudabous, Wissem Ben Azzouz, Hadhami Ben Turkia, Salima Ferchichi, Neji Tebib, Taieb Massoud, Mohamed Ghorbel and Sandrine Laradi
    Citation: Diagnostic Pathology 2022 17:44
  18. Authors: Yumiko Hori, Katsutoshi Hirose, Michio Ozeki, Kenji Hata, Daisuke Motooka, Shinichiro Tahara, Takahiro Matsui, Masaharu Kohara, Hiroki Higashihara, Yusuke Ono, Kaishu Tanaka, Satoru Toyosawa and Eiichi Morii
    Citation: Diagnostic Pathology 2022 17:43

    The original article was published in Diagnostic Pathology 2022 17:19

  19. Extraskeletal myxoid chondrosarcomas (EMCs) are solid tumors that have been genetically and biologically characterized. Only a few studies have discussed the role of the KIT gene or CD117 expression in EMCs, iden...

    Authors: Chen Wang, Zhi-Jie You, Xiao-Yan Chen, Jie Lin and Yi-Juan Wu
    Citation: Diagnostic Pathology 2022 17:42
  20. Distinguishing benign lesion from early malignancy in melanocytic lesions of the nail unit still remains a diagnostic challenge, both clinically and histopathologically. While several immunohistochemistry (IHC...

    Authors: Young Jae Kim, Chang Jin Jung, Hyoungmin Na, Woo Jin Lee, Sung Eun Chang, Mi Woo Lee, Chan-Sik Park, Youngkyoung Lim and Chong Hyun Won
    Citation: Diagnostic Pathology 2022 17:41
  21. To explore whether the “WSI Stitcher”, a program we developed for reconstructing virtual large slide through whole slide imaging fragments stitching, can improve the efficiency and consistency of pathologists ...

    Authors: Dandan Han, Jun Liao, Meng Zhang, Chenchen Qin, Mengxue Han, Chun Wu, Jinze Li, Jianhua Yao and Yueping Liu
    Citation: Diagnostic Pathology 2022 17:40
  22. IFI16 plays an important role in innate immunity against invasive microbial infection by sensing double-stranded DNA viruses due to caspase-1-dependent inflammasome activation and subsequent maturation and sec...

    Authors: Li Liu, Shuangshuang Xie, Cheng Li, Yue Guo, Xiaoyan Liu, Xiuhua Zhao, Qiang Li and Wenjun Du
    Citation: Diagnostic Pathology 2022 17:39
  23. The occurrence of endocrine cell micronests in ovarian tumors is rarely reported. To our knowledge, there are only three prior cases reported to date: one occurring in an ovarian mucinous cystadenoma, one in a...

    Authors: Katrina Collins, Sheila Segura and Michael Hwang
    Citation: Diagnostic Pathology 2022 17:37
  24. The early detection of coronavirus disease (COVID-19) infection to improve disease management becomes the greatest challenge. Despite the high sensitivity of RT-PCR, not only it was reported that 20–67% of inf...

    Authors: Somaye Ghasemi, Narges Nazari Harmooshi and Fakher Rahim
    Citation: Diagnostic Pathology 2022 17:36
  25. Hemangioblastoma is an indolent mesenchymal tumor most frequently occurring in the central nervous system (CNS), but can also arise extraneuraxially, as part of Von Hippel-Lindau (VHL) disease or in sporadic t...

    Authors: Xintong Wang, George K. Haines III, Meenakshi Mehrotra, Jane Houldsworth and Qiusheng Si
    Citation: Diagnostic Pathology 2022 17:34
  26. Most of malignant melanomas originate from skin and often metastasize to the lungs, rarely metastasizes to the liver and bone. However, imageology characters of lung metastasis tumor are commonly similar to th...

    Authors: Juan Sun, Yun-Zhu Zhu, Pan-Pan Shao, Jing Ke, Wei Wang, Qiu-Lin Sun, Jia-Bin Li and Jun Cheng
    Citation: Diagnostic Pathology 2022 17:33
  27. To improve identification of patients with cutaneous squamous cell carcinoma (SCC) at high risk for metastatic disease, the DecisionDx-SCC assay, a prognostic 40-gene expression profile (40-GEP) test, was deve...

    Authors: Sherri Borman, Jeff Wilkinson, Lauren Meldi-Sholl, Clare Johnson, Kelsey Carter, Kyle R. Covington, Alison L. Fitzgerald, Sarah J. Kurley, Aaron S. Farberg, Matthew S. Goldberg, Federico A. Monzon, Kristen Oelschlager and Robert W. Cook
    Citation: Diagnostic Pathology 2022 17:32
  28. Despite a reported cardiac injury in patients with new coronavirus infection, the possibility and specifics of genuine viral myocarditis in COVID-19 remains not fully clear.

    Authors: Evgeniya Kogan, Yuriy Berezovskiy, Olga Blagova, Anna Kukleva, Lyudmila Semyonova, Evgeniy Gretsov and Atadzhan Ergeshov
    Citation: Diagnostic Pathology 2022 17:31
  29. Pulmonary enteric adenocarcinoma (PEAC) has distinctive clinical outcomes, radiographic, pathological and molecular characteristics. The prognosis of patients with PEAC was poor. However, molecular profiles an...

    Authors: Min Xie, Dong Chen, Yong Li, Xiansheng Liu, Dong Kuang and Xiaochen Li
    Citation: Diagnostic Pathology 2022 17:30
  30. SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily A, member 4-deficient thoracic sarcoma (SMARCA4-DTS) is a rare disease that has recently been described as an entity. It is...

    Authors: Yusuke Kito, Keisuke Kawashima, Chiemi Saigo, Masayoshi Hasegawa, Shusuke Nomura, Takuya Mikamo, Yuki Hanamatsu, Yasuhiro Matsuo and Tamostu Takeuchi
    Citation: Diagnostic Pathology 2022 17:29
  31. The underlying mechanism of IgA vasculitis (IgAV) and IgA vasculitis with nephritis (IgAVN) remains unclear. Therefore, there are no accurate diagnostic methods. Lipid metabolism is related to many immune rela...

    Authors: Ying Liu, Min Wen, Qingnan He, Xiqiang Dang, Shipin Feng, Taohua Liu, Xuewei Ding, Xiaoyan Li and Xiaojie He
    Citation: Diagnostic Pathology 2022 17:28
  32. Anaplastic lymphoma kinase (ALK) gene rearrangements, have been identified in approximately 2-7% of patients with lung adenocarcinoma (LUAD). However, co-occurrence of double ALK fusions in one patient was rare. ...

    Authors: Hong Tao, Zhe Liu, Jing Mu, Fei Gai, Zhan Huang and Liang Shi
    Citation: Diagnostic Pathology 2022 17:27
  33. Large cell neuroendocrine carcinoma (LCNEC) is a high-grade malignant pulmonary neuroendocrine tumour. The distinction of pulmonary large cell carcinoma (LCC) and LCNEC is based on the presence of neuroendocri...

    Authors: Zuoyu Liang, Weiya Wang, Qianrong Hu, Ping Zhou, Ying Zhang, Yuan Tang, Qian Wu, Yiyun Fu, Xue Li, Yang Shao and Lili Jiang
    Citation: Diagnostic Pathology 2022 17:26
  34. Pulmonary carcinoid tumors rarely coexist with non-small cell lung carcinoma, and only nine cases have been reported previously. The pathogenesis and origin of these combined tumors remain unclear because of i...

    Authors: Chihiro Inoue, Sachiko Konosu-Fukaya, Kazuhiro Murakami, Ryoko Saito-Koyama, Hirofumi Watanabe, Hideki Mitomo, Naoya Ishibashi, Takafumi Sugawara, Toshiharu Tabata, Hironobu Sasano and Yasuhiro Nakamura
    Citation: Diagnostic Pathology 2022 17:25
  35. Currently, breast cancers are divided into four major molecular subtypes. The distinction between the luminal A and luminal B subtypes is mainly based on the cellular proliferation indices and is assessed by t...

    Authors: Dorsay Sadeghian, Hana Saffar, Pouya Mahdavi Sharif, Vahid Soleimani and Behnaz Jahanbin
    Citation: Diagnostic Pathology 2022 17:24
  36. The incidence of tongue cancer in young adults is on the rise. This trend is more pronounced in females. Although the aetiology is still unclear, there is mounting evidence that genetic syndromes can play a ke...

    Authors: Takako Eva Yabe, Kylie King, Susan Russell, Laveniya Satgunaseelan, Ruta Gupta, James Chen and Bruce Ashford
    Citation: Diagnostic Pathology 2022 17:23
  37. SWItch Sucrose Non-Fermentable (SWI/SNF) chromatin-remodeling complex functions collectively as a tumor suppressor and the inactivation of any of its constituent components is frequently associated with tumor ...

    Authors: Wenjuan Xu, Haiying Dong, Guoqing Ru and Ming Zhao
    Citation: Diagnostic Pathology 2022 17:22
  38. Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) is a strong cancer stem cell marker in colorectal cancer; however, there are many unclear aspects of LGR5 expression in pancreatic cancer. It has...

    Authors: Masato Kamakura, Takeshi Uehara, Mai Iwaya, Shiho Asaka, Shota Kobayashi, Tomoyuki Nakajima, Yasuhiro Kinugawa, Tadanobu Nagaya, Takahiro Yoshizawa, Akira Shimizu, Hiroyoshi Ota and Takeji Umemura
    Citation: Diagnostic Pathology 2022 17:21
  39. Ki-67 standard reference card (SRC) and artificial intelligence (AI) software were used to evaluate breast cancer Ki-67LI. We established training and validation sets and studied the repeatability inter-observ...

    Authors: Lina Li, Dandan Han, Yongqiang Yu, Jinze Li and Yueping Liu
    Citation: Diagnostic Pathology 2022 17:20
  40. Fibro-adipose vascular anomaly (FAVA) is a rare and new entity of vascular anomaly. Activating mutations in the phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) gene were identified...

    Authors: Yumiko Hori, Katsutoshi Hirose, Michio Ozeki, Kenji Hata, Daisuke Motooka, Shinichiro Tahara, Takahiro Matsui, Masaharu Kohara, Hiroki Higashihara, Yusuke Ono, Kaishu Tanaka, Satoru Toyosawa and Eiichi Morii
    Citation: Diagnostic Pathology 2022 17:19

    The Correction to this article has been published in Diagnostic Pathology 2022 17:43

  41. As a rare salivary gland malignancy, clear cell carcinoma (CCC) is easily misdiagnosed. This study identified the features that allow better recognition of the clinicopathological and molecular characteristics...

    Authors: Lanlan Xuan, Suxia Wang, Jianguo Wei, Jianwei Yuan and Honggang Liu
    Citation: Diagnostic Pathology 2022 17:18
  42. Immunohistochemistry (IHC) using monoclonal and polyclonal antibodies is a useful diagnostic method for detecting pathogen antigens in fixed tissues, complementing the direct diagnosis of infectious diseases b...

    Authors: Hamadou Oumarou Hama, Gérard Aboudharam, Rémi Barbieri, Hubert Lepidi and Michel Drancourt
    Citation: Diagnostic Pathology 2022 17:17

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