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Diagnostic Pathology

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  1. Content type: Case Report

    Although adenocarcinomas showing neuroendocrine differentiation or those mixed with high-grade neuroendocrine carcinoma (NEC) are sometimes encountered, composite tumors comprising neuroendocrine tumor (NET) G...

    Authors: Hiromi Kanno-Okada, Tomoko Mitsuhashi, Katsuhiro Mabe, Tadakazu Shimoda and Yoshihiro Matsuno

    Citation: Diagnostic Pathology 2017 12:85

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  2. Content type: Research

    Hematoxylin-eosin (HE) staining of a full-thickness rectal wall fragment is classically used for the diagnosis of Hirschsprung disease (HD). However, this technique requires large fragments for a better diagno...

    Authors: Suellen Serafini, Maria Mercês Santos, Ana Cristina Aoun Tannuri, Maria Claudia Nogueira Zerbini, Maria Cecília de Mendonça Coelho, Josiane de Oliveira Gonçalves and Uenis Tannuri

    Citation: Diagnostic Pathology 2017 12:84

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  3. Content type: Case Report

    Plasmablastic lymphoma (PBL) is relatively new clinical entity described as a distinct subtype of diffuse large B-cell lymphoma (DLBCL). It is characterized by its aggressive nature and proliferation of large ...

    Authors: Ita Hadžisejdić, Emina Babarović, Luka Vranić, Antica Duletić Načinović, Ksenija Lučin, Maja Krašević and Nives Jonjić

    Citation: Diagnostic Pathology 2017 12:83

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  4. Content type: Case Report

    KIAA1549-BRAF fusion is the most common genetic event in pilocytic astrocytoma (PA), and leads to activation of the mitogen activated protein kinase (MAPK) signaling pathway. Fusions o...

    Authors: Jeffrey Helgager, Hart G. Lidov, Navin R. Mahadevan, Mark W. Kieran, Keith L. Ligon and Sanda Alexandrescu

    Citation: Diagnostic Pathology 2017 12:82

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  5. Content type: Case Report

    TP53 mutations are rarely identified in low grade endometrioid carcinoma of the endometrium, and their pathogenic significance in such tumors is evidenced by the fact that TP53 aberrat...

    Authors: Oluwole Fadare and Vinita Parkash

    Citation: Diagnostic Pathology 2017 12:81

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  6. Content type: Research

    Steatosis is routinely assessed histologically in clinical practice and research. Automated image analysis can reduce the effort of quantifying steatosis. Since reproducibility is essential for practical use, ...

    Authors: André Homeyer, Patrik Nasr, Christiane Engel, Stergios Kechagias, Peter Lundberg, Mattias Ekstedt, Henning Kost, Nick Weiss, Tim Palmer, Horst Karl Hahn, Darren Treanor and Claes Lundström

    Citation: Diagnostic Pathology 2017 12:80

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  7. Content type: Case Report

    Maffucci syndrome is a congenital, non-hereditary mesodermal dysplasia characterized by multiple enchondromas and hemangiomas. The presence of visceral vascular lesions in this syndrome is exceedingly rare.

    Authors: Xiao-Dan Huang, Hao-Sen Jiao, Zheng Yang, Chuang-Qi Chen, Yu-Long He and Xin-Hua Zhang

    Citation: Diagnostic Pathology 2017 12:79

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  8. Content type: Research

    Composite intestinal adenoma-microcarcinoid (CIAM) is a rare colorectal lesion that mostly comprises a conventional adenomatous component with a minute proportion of neuroendocrine (NE) component. Although mic...

    Authors: Mi-Jung Kim, Eun-Jung Lee, Do Sun Kim, Doo Han Lee, Eui Gon Youk and Hyun-Jung Kim

    Citation: Diagnostic Pathology 2017 12:78

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  9. Content type: Case Report

    Renal cell carcinoma most commonly metastasizes to the lungs, skeleton or liver. Metastatic renal cell carcinoma to the breast is very rare, especially for clear cell carcinoma, and few cases regarding this co...

    Authors: Yanjun Xu, Rui Hou, Qijie Lu, Yifan Deng and Bin Hu

    Citation: Diagnostic Pathology 2017 12:76

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  10. Content type: Case Report

    A small number of rhabdomyosarcoma (RMS) cases involve the bone marrow. A leukemic presentation of RMS has been reported in a few case series, although almost all cases of leukemic RMS are not completely mimic...

    Authors: Osamu Imataki, Makiko Uemura, Shumpei Uchida, Shigeyuki Yokokura, Akihiro Takeuchi, Ryo Ishikawa, Akihiro Kondo, Kayoko Seo and Norimitsu Kadowaki

    Citation: Diagnostic Pathology 2017 12:77

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  11. Content type: Case Report

    Spontaneous isolated dissection of the superior mesenteric artery (SMA) can lead to bowel ischemia, aneurysm rupture, or even death. Studies have suggested that mechanical or hemodynamic stress on the vascular...

    Authors: Nobuhiro Akuzawa, Makoto Kurabayashi, Tsukasa Suzuki, Daisuke Yoshinari, Mitsunobu Kobayashi, Yoshifumi Tanahashi, Fujio Makita and Ryusei Saito

    Citation: Diagnostic Pathology 2017 12:74

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  12. Content type: Case Report

    Dieulafoy’s lesion, also known as a caliber-persistent artery, is a shallow, small, and rare lesion that occurs along the lesser curvature of proximal stomach. It is rare for a Dieulafoy’s lesion to present as...

    Authors: Hsi-Lan Huang, Chi Yan Leung and Chien-Jui Cheng

    Citation: Diagnostic Pathology 2017 12:73

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  13. Content type: Research

    Immune checkpoint blockade targeting PD-1/PD-L1 has shown efficacy in several types of cancers. However, the correlation between PD-L1/PD-1 expression and the specific clinicopathological features in papillary...

    Authors: Yanhua Bai, Dongfeng Niu, Xiaozheng Huang, Ling Jia, Qiang Kang, Fangyuan Dou, Xinqiang Ji, Weicheng Xue, Yiqiang Liu, Zhongwu Li, Qin Feng, Dongmei Lin and Kennichi Kakudo

    Citation: Diagnostic Pathology 2017 12:72

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  14. Content type: Case Report

    Hyalinizing clear cell carcinoma (HCCC) is a rare low-grade tumour of salivary glands that was first described as a distinct entity in 1994 by Milchgrub et al. EWSR1-ATF1 fusion was found to be specific for this ...

    Authors: Batool M. AlAli, Mohammed J. Alyousef, Ahmad Salah Kamel, Mohammad A. Al hamad, Mohammad H. Al-Bar and Roaa M. Algowiez

    Citation: Diagnostic Pathology 2017 12:70

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  15. Content type: Research

    Immune cell infiltrates (ICI) of tumors are scored by pathologists around tumor glands. To obtain a better understanding of the immune infiltrate, individual immune cell types, their activation states and loca...

    Authors: Zhaoxuan Ma, Stephen L. Shiao, Emi J. Yoshida, Steven Swartwood, Fangjin Huang, Michael E. Doche, Alice P. Chung, Beatrice S. Knudsen and Arkadiusz Gertych

    Citation: Diagnostic Pathology 2017 12:69

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  16. Content type: Case Report

    Inflammatory myofibroblastic tumor (IMT) of the stomach is extremely rare in adults and exhibits a variable biological behavior that ranges from frequently benign lesions to more aggressive variants. Here we r...

    Authors: Jun Fan, Bo Huang, Xiuping Yang, Ming Yang, Jun He and Xiu Nie

    Citation: Diagnostic Pathology 2017 12:68

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  17. Content type: Methodology

    Precise prognostic and predictive variables allowing improved post-operative treatment stratification are missing in patients treated for stage II colon cancer (CC). Investigation of tumor infiltrating lymphoc...

    Authors: Ann C. Eriksen, Johnnie B. Andersen, Martin Kristensson, René dePont Christensen, Torben F. Hansen, Sanne Kjær-Frifeldt and Flemming B. Sørensen

    Citation: Diagnostic Pathology 2017 12:65

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  18. Content type: Research

    Immunohistochemical staining with conventional anti-β-catenin antibody has been applied as a diagnostic tool for desmoid-type fibromatosis (DF). This study aimed to evaluate the diagnostic and prognostic value...

    Authors: Tomohisa Sakai, Yoshihiro Nishida, Shunsuke Hamada, Hiroshi Koike, Kunihiro Ikuta, Takehiro Ota and Naoki Ishiguro

    Citation: Diagnostic Pathology 2017 12:66

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  19. Content type: Case Report

    Mesonephric adenocarcinoma (MA) is a rare tumor believed to arise from mesonephric remnants occurring mostly in the uterine cervix and, to a lesser extent, the corpus. Since the first case report of MA in the ...

    Authors: Hiroka Ando, Yuko Watanabe, Minori Ogawa, Hiromi Tamura, Tomomi Deguchi, Kayo Ikeda, Mayumi Fujitani, Mitsunori Shioji, Tomoko Tsujie, Reiko Doi, Akinori Wakimoto and Shiro Adachi

    Citation: Diagnostic Pathology 2017 12:63

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  20. Content type: Case Report

    Intravascular large B-cell lymphoma (IVLBCL) is a subtype of diffuse large B-cell lymphoma (DLBCL) that is rare and highly aggressive and that may progressively involve many organs. CNS (central nervous system...

    Authors: Bo Luo, Jia-mei Chen, Jie Liu, Wen-he Li, Yu-xiang Shi, Pan Zeng, Yong-hui Xie and Hong-feng Zhang

    Citation: Diagnostic Pathology 2017 12:64

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  21. Content type: Research

    Ciliated muconodular papillary tumors (CMPTs) are newly recognized rare peripheral lung nodules that are histologically characterized by ciliated columnar, goblet, and basal cells. Although recent studies have...

    Authors: Emiko Udo, Bungo Furusato, Kazuko Sakai, Leah M Prentice, Tomonori Tanaka, Yuka Kitamura, Tomoshi Tsuchiya, Naoya Yamasaki, Takeshi Nagayasu, Kazuto Nishio and Junya Fukuoka

    Citation: Diagnostic Pathology 2017 12:62

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  22. Content type: Case Report

    Abernethy malformation is a rare congenital anomaly characterised by the partial or complete absence of the portal vein and the subsequent development of an extrahepatic portosystemic shunt. Caroli’s disease i...

    Authors: Xiao-xiao Mi, Xiao-guang Li, Zi-rong Wang, Ling Lin, Chun-hai Xu and Jun-ping Shi

    Citation: Diagnostic Pathology 2017 12:61

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