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  1. Case Report

    Spontaneous isolated dissection of the superior mesenteric artery and aneurysm formation resulting from segmental arterial mediolysis: a case report

    Spontaneous isolated dissection of the superior mesenteric artery (SMA) can lead to bowel ischemia, aneurysm rupture, or even death. Studies have suggested that mechanical or hemodynamic stress on the vascular...

    Nobuhiro Akuzawa, Makoto Kurabayashi, Tsukasa Suzuki, Daisuke Yoshinari, Mitsunobu Kobayashi, Yoshifumi Tanahashi, Fujio Makita and Ryusei Saito

    Diagnostic Pathology 2017 12:74

    Published on: 16 October 2017

  2. Research

    PD-L1 and PD-1 expression are correlated with distinctive clinicopathological features in papillary thyroid carcinoma

    Immune checkpoint blockade targeting PD-1/PD-L1 has shown efficacy in several types of cancers. However, the correlation between PD-L1/PD-1 expression and the specific clinicopathological features in papillary...

    Yanhua Bai, Dongfeng Niu, Xiaozheng Huang, Ling Jia, Qiang Kang, Fangyuan Dou, Xinqiang Ji, Weicheng Xue, Yiqiang Liu, Zhongwu Li, Qin Feng, Dongmei Lin and Kennichi Kakudo

    Diagnostic Pathology 2017 12:72

    Published on: 3 October 2017

  3. Case Report

    Primary paranasal sinus hyalinizing clear cell carcinoma: a case report

    Hyalinizing clear cell carcinoma (HCCC) is a rare low-grade tumour of salivary glands that was first described as a distinct entity in 1994 by Milchgrub et al. EWSR1-ATF1 fusion was found to be specific for this ...

    Batool M. AlAli, Mohammed J. Alyousef, Ahmad Salah Kamel, Mohammad A. Al hamad, Mohammad H. Al-Bar and Roaa M. Algowiez

    Diagnostic Pathology 2017 12:70

    Published on: 25 September 2017

  4. Research

    Data integration from pathology slides for quantitative imaging of multiple cell types within the tumor immune cell infiltrate

    Immune cell infiltrates (ICI) of tumors are scored by pathologists around tumor glands. To obtain a better understanding of the immune infiltrate, individual immune cell types, their activation states and loca...

    Zhaoxuan Ma, Stephen L. Shiao, Emi J. Yoshida, Steven Swartwood, Fangjin Huang, Michael E. Doche, Alice P. Chung, Beatrice S. Knudsen and Arkadiusz Gertych

    Diagnostic Pathology 2017 12:69

    Published on: 18 September 2017

  5. Methodology

    Computer-assisted stereology and automated image analysis for quantification of tumor infiltrating lymphocytes in colon cancer

    Precise prognostic and predictive variables allowing improved post-operative treatment stratification are missing in patients treated for stage II colon cancer (CC). Investigation of tumor infiltrating lymphoc...

    Ann C. Eriksen, Johnnie B. Andersen, Martin Kristensson, René dePont Christensen, Torben F. Hansen, Sanne Kjær-Frifeldt and Flemming B. Sørensen

    Diagnostic Pathology 2017 12:65

    Published on: 29 August 2017

  6. Research

    Immunohistochemical staining with non-phospho β-catenin as a diagnostic and prognostic tool of COX-2 inhibitor therapy for patients with extra-peritoneal desmoid-type fibromatosis

    Immunohistochemical staining with conventional anti-β-catenin antibody has been applied as a diagnostic tool for desmoid-type fibromatosis (DF). This study aimed to evaluate the diagnostic and prognostic value...

    Tomohisa Sakai, Yoshihiro Nishida, Shunsuke Hamada, Hiroshi Koike, Kunihiro Ikuta, Takehiro Ota and Naoki Ishiguro

    Diagnostic Pathology 2017 12:66

    Published on: 29 August 2017

  7. Case Report

    Mesonephric adenocarcinoma of the uterine corpus with intracystic growth completely confined to the myometrium: a case report and literature review

    Mesonephric adenocarcinoma (MA) is a rare tumor believed to arise from mesonephric remnants occurring mostly in the uterine cervix and, to a lesser extent, the corpus. Since the first case report of MA in the ...

    Hiroka Ando, Yuko Watanabe, Minori Ogawa, Hiromi Tamura, Tomomi Deguchi, Kayo Ikeda, Mayumi Fujitani, Mitsunori Shioji, Tomoko Tsujie, Reiko Doi, Akinori Wakimoto and Shiro Adachi

    Diagnostic Pathology 2017 12:63

    Published on: 25 August 2017

  8. Case Report

    A case of intravascular large B cell lymphoma presenting as nodular goiter

    Intravascular large B-cell lymphoma (IVLBCL) is a subtype of diffuse large B-cell lymphoma (DLBCL) that is rare and highly aggressive and that may progressively involve many organs. CNS (central nervous system...

    Bo Luo, Jia-mei Chen, Jie Liu, Wen-he Li, Yu-xiang Shi, Pan Zeng, Yong-hui Xie and Hong-feng Zhang

    Diagnostic Pathology 2017 12:64

    Published on: 25 August 2017

  9. Research

    Ciliated muconodular papillary tumors of the lung with KRAS/BRAF/AKT1 mutation

    Ciliated muconodular papillary tumors (CMPTs) are newly recognized rare peripheral lung nodules that are histologically characterized by ciliated columnar, goblet, and basal cells. Although recent studies have...

    Emiko Udo, Bungo Furusato, Kazuko Sakai, Leah M Prentice, Tomonori Tanaka, Yuka Kitamura, Tomoshi Tsuchiya, Naoya Yamasaki, Takeshi Nagayasu, Kazuto Nishio and Junya Fukuoka

    Diagnostic Pathology 2017 12:62

    Published on: 22 August 2017

  10. Review

    Pleural epithelioid angiosarcoma with lymphatic differentiation arisen after radiometabolic therapy for thyroid carcinoma: immunohistochemical findings and review of the literature

    Pleural angiosarcoma is a rare tumor that causes diffuse pleural thickening and effusion, mimicking mesothelioma. Immunohistochemistry is needed to highlight endothelial differentiation. We describe the first ...

    Daniela Cabibi, Giulia Pipitone, Rossana Porcasi, Sabrina Ingrao, Ignazio Benza, Calogero Porrello, Massimo Cajozzo and Antonino Giulio Giannone

    Diagnostic Pathology 2017 12:60

    Published on: 15 August 2017

  11. Research

    Gene expression profiling in uveal melanoma: technical reliability and correlation of molecular class with pathologic characteristics

    A 15-gene expression profile test has been clinically validated and is widely utilized in newly diagnosed uveal melanoma (UM) patients to assess metastatic potential of the tumor. As most patients are treated ...

    Kristen M. Plasseraud, Jeff K. Wilkinson, Kristen M. Oelschlager, Trisha M. Poteet, Robert W. Cook, John F. Stone and Federico A. Monzon

    Diagnostic Pathology 2017 12:59

    Published on: 4 August 2017

  12. Research

    Variation of stemness markers expression in tumor nodules from synchronous multi-focal hepatocellular carcinoma – an immunohistochemical study

    Advancing knowledge in molecular pathogenesis of hepatocellular carcinoma (HCC) opens up new horizons in the diagnostic, prognostic and therapeutic perspectives. Assessing the expression of molecular targets p...

    Regina Cheuk-lam Lo, Carmen Oi-ning Leung, Kenneth Siu-ho Chok and Irene Oi-lin Ng

    Diagnostic Pathology 2017 12:56

    Published on: 1 August 2017

  13. Research

    Level of mitoses in non-muscle invasive papillary urothelial carcinomas (pTa and pT1) at initial bladder biopsy is a simple and powerful predictor of clinical outcome: a multi-center study in South Korea

    Histologic grade is the most important predictor of the clinical outcome of non-muscle invasive (Ta, T1) papillary urothelial carcinoma (NMIPUCa), but its ambiguous criteria diminish its power to predict recur...

    Ji Eun Kwon, Nam Hoon Cho, Yeong-Jin Choi, So Dug Lim, Yong Mee Cho, Sun Young Jun, Sanghui Park, Young A. Kim, Sung-Sun Kim, Mi Sun Choe, Jung-dong Lee, Dae Yong Kang, Jae Y. Ro and Hyun-Jung Kim

    Diagnostic Pathology 2017 12:54

    Published on: 24 July 2017

  14. Research

    GATA3 is a sensitive marker for primary genital extramammary paget disease: an immunohistochemical study of 72 cases with comparison to gross cystic disease fluid protein 15

    GATA-binding protein 3 (GATA3) has been identified as a sensitive marker for breast carcinoma but its sensitivity in primary genital extramammary Paget diseases (EMPDs) has not been well studied.

    Ming Zhao, Lixin Zhou, Li Sun, Yan Song, Yunquan Guo, Xun Zhang, Feng Zhao, Peng Wang, Junqiu Yue, Dongfeng Niu, Zhongwu Li, Xiaozheng Huang, Qiang Kang, Lin Jia, Jinping Lai and Dengfeng Cao

    Diagnostic Pathology 2017 12:51

    Published on: 10 July 2017

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