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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. ROS1 fusion is an infrequent, but attractive target for therapy in patients with metastatic non- small-cell lung cancer. In studies on mainly late-stage disease, the prevalence of ROS1 fusions is about 1–3%. I...

    Authors: Anne Pernille Harlem Dyrbekk, Abdirashid Ali Warsame, Pål Suhrke, Marianne Odnakk Ludahl, Joakim Oliu Moe, Inger Johanne Zwicky Eide, Marius Lund-Iversen and Odd Terje Brustugun
    Citation: Diagnostic Pathology 2023 18:70
  2. Primary thyroid lymphoma (PTL) is a rare cancer accounting for approximately 5% of thyroid malignancies. Historically, incisional biopsy has been the gold standard for definitive diagnosis of PTL, however, the...

    Authors: Alexander D. Karabachev, William J. Brundage, Mirabelle B. Sajisevi and Allison L. Ciolino
    Citation: Diagnostic Pathology 2023 18:69
  3. Low- and middle-income countries (LMICs) represent a big source of data not only for endemic diseases but also for neoplasms. Data is the fuel which drives the modern era. Data when stored in digital form can ...

    Authors: Talat Zehra, Anil Parwani, Jamshid Abdul-Ghafar and Zubair Ahmad
    Citation: Diagnostic Pathology 2023 18:68
  4. Deep learning models applied to healthcare applications including digital pathology have been increasing their scope and importance in recent years. Many of these models have been trained on The Cancer Genome ...

    Authors: Taher Dehkharghanian, Azam Asilian Bidgoli, Abtin Riasatian, Pooria Mazaheri, Clinton J. V. Campbell, Liron Pantanowitz, H. R. Tizhoosh and Shahryar Rahnamayan
    Citation: Diagnostic Pathology 2023 18:67
  5. Mesothelioma, with various clinical manifestations, radiological features, and histomorphological types, can be divided into epithelioid, sarcomatoid, and biphasic types, according to their histomorphological ...

    Authors: Wang RanYue, Wu ChunYan, Hou Likun, Zhang LiPing, Lin JieLu and Dong ZhengWei
    Citation: Diagnostic Pathology 2023 18:64
  6. Authors: Jung Hee Lee, Yong Jun Kim, Hyun Woo Ryu, Seung Won Shin, Eun Ji Kim, So Hyun Shin, Joon Young Park, So Young Kim, Chung Su Hwang, Joo‑Young Na, Dong Hoon Shin, Jee Yeon Kim and Hyun Jung Lee
    Citation: Diagnostic Pathology 2023 18:63

    The original article was published in Diagnostic Pathology 2023 18:36

  7. SMARCA4-deficient undifferentiated uterine sarcoma (SDUS) is a highly invasive single-gene malignant tumor caused by mutations in the SMARCA4 gene. SDUS has a poor prognosis, with no established treatment strateg...

    Authors: Jie Gao, Ruirui Fan, Dahong Chen, Jinlin Hou, Hanlin Chen and Mingzhi Lu
    Citation: Diagnostic Pathology 2023 18:62
  8. Testicular Sertoli cell tumor (SCT) is very rare sex cord-gonadal stromal tumor, and sclerosing SCT (SSCT) is even rarer. So far, no more than 50 cases of SSCT have been reported. 80% of SSCTs are less than 2 ...

    Authors: Xueyao Tang, Yifan Hu, Hong Zhou and Yang Zhou
    Citation: Diagnostic Pathology 2023 18:61
  9. Cancer metastasis to the kidney is a rare event. We retrospectively analyzed clinicopathologic characteristics in 6 cases of diagnosed renal metastases from primary lung cancer. We also provide clinical follow...

    Authors: Hui Lian, Xinyu Pan, Bo Hong, Jie Min and Fengbo Huang
    Citation: Diagnostic Pathology 2023 18:60
  10. Spindle cell tumors, called solitary fibrous tumors (SFTs), are of mesenchymal origin, and can develop in the orbit. As ‘intermediate malignancy’ tumors, only a small percentage show malignant behavior, such a...

    Authors: Qi Zhou, Yuting Liu, Fang Wang, Yang Cao, Hongbin Lv and Xibo Zhang
    Citation: Diagnostic Pathology 2023 18:59
  11. Authors: Bindu H. Akkanti, Rahat Hussain, Manish K. Patel, Jayeshkumar A. Patel, Kha Dinh, Bihong Zhao, Shaimaa Elzamly, Kevin Pelicon, Klemen Petek, Ismael A. Salas de Armas, Mehmet Akay, Biswajit Kar, Igor D. Gregoric and L. Maximilian Buja
    Citation: Diagnostic Pathology 2023 18:58

    The original article was published in Diagnostic Pathology 2020 15:83

  12. Angiomyolipoma is a benign mesenchymal neoplasm of a wide histological heterogeneity belonging to the PEComa “family.” The liver, after the kidney, is their second most frequent location. However, inflammatory...

    Authors: Francisco Javier Velasco-Albendea, María Jesús Gil-Belmonte, Beatriz Estébanez-Ferrero, Orlando Fuentes-Porcel and Bruno José Nievas-Soriano
    Citation: Diagnostic Pathology 2023 18:57
  13. The concept of critical value is not evident in surgical pathology, and there is no established protocol for determining, reporting, and documenting these results.

    Authors: Neda Soleimani, Atefe Zare Sheibani, Samira Khajeh, Sahand Mohammadzadeh, Negar Taheri, Maral Mokhtari, Mahsa Farhadi, Zahra Hajizade, Saeideh Khaleghpanah and Sima Dehghani
    Citation: Diagnostic Pathology 2023 18:55
  14. Histomorphological differentiation between pancreatic serous cystadenoma (SCA) and clear cell renal cell carcinoma (RCC) can be challenging. We aimed to study Paired box 8 protein (Pax8) expression profile in ...

    Authors: Zhikai Chi, Jing Xu, Dipti M. Karamchandani and Lan Peng
    Citation: Diagnostic Pathology 2023 18:54
  15. Eosinophilic solid and cystic renal cell carcinoma (ESC-RCC) is an under-recognized, emerging new entity of sporadic renal neoplasms, which is listed as a rare type of renal cell carcinoma in the 2022 WHO rena...

    Authors: Xin He, Ying Chen, Hao Tang, Yujuan Xu, Xingyan Zhu, Caihong Wang, Qiang Chen and Deyu Guo
    Citation: Diagnostic Pathology 2023 18:53
  16. Breast-implant associated (BIA) lymphoma is an infrequent type of cancer occurring in the fluid and fibrous capsule around a textured breast implant. Recently, both the 2022 WHO 5th edition classification of H...

    Authors: Johanna Vets, Lukas Marcelis, Charlotte Schepers, Yaliva Dorreman, Sanne Verbeek, Lieve Vanwalleghem, Katrien Gieraerts, Liesbeth Meylaerts, Jan Lesaffer, Helena Devos, Natalie Put, Sylvia Snauwaert, Pascale De Paepe and Thomas Tousseyn
    Citation: Diagnostic Pathology 2023 18:52
  17. Head and neck squamous cell carcinoma (HNSCC) is a multisite malignancy that responds well to immunotherapy. Despite the initial enthusiasm, the clinical benefits of immunotherapy in HNSCC patients are overall...

    Authors: Xinlong Fan, Xiao Yang, Nan Guo, Xin Gao and Yuejiao Zhao
    Citation: Diagnostic Pathology 2023 18:51
  18. Mucinous carcinoma (MC) is a histological subtype of ovarian cancer that has a worse prognosis at advanced stages than the most prevalent histological subtype, high-grade serous carcinomas. Invasive patterns h...

    Authors: Taira Hada, Morikazu Miyamoto, Yuka Ohtsuka, Jin Suminokura, Tsubasa Ito, Naohisa Kishimoto, Soko Nishitani, Minori Takada, Akari Imauji, Risa Tanabe and Masashi Takano
    Citation: Diagnostic Pathology 2023 18:49
  19. Determination of programmed death-ligand 1 (PD-L1) protein expression level in tumor cells and tumor-associated immune cells is critical for identifying patients eligible for immunotherapy. PD-L1 manual scorin...

    Authors: Chunyan Liu, Fang Fang, Ying Kong and Ehab A. ElGabry
    Citation: Diagnostic Pathology 2023 18:48
  20. Struma ovarii is an unusual ovarian teratoma containing predominantly thyroid tissue. Less than 10% of cases undergo malignant transformation in the thyroid tissue and are considered malignant struma ovarii (M...

    Authors: Gabriella T. Seo, Jeremy Minkowitz, Danielle A. Kapustin, Jun Fan, Gerald Minkowitz, Miriam Minkowitz, Eric Dowling, Ammar Matloob, Divya Asti, Meekoo Dhar, Christopher Shutty, Alan Brickman, Mark L. Urken, Margaret Brandwein-Weber and Sydney D. Finkelstein
    Citation: Diagnostic Pathology 2023 18:47
  21. Hypoxia is a characteristic of many solid tumours and an adverse prognostic factor for cancer therapy. Hypoxia results in upregulation of carbonic anhydrase IX (CAIX) expression, a pH-regulating enzyme. Many h...

    Authors: Suad A. K. Shamis, Joanne Edwards and Donald C. McMillan
    Citation: Diagnostic Pathology 2023 18:46
  22. Malignant perivascular epithelioid cell tumors (PEComas) are exceedingly rare malignant mesenchymal neoplasms with characteristic morphological and immunohistochemical (IHC) patterns. However, some malignant P...

    Authors: Luke Meredith, Timothy Chao, Avinoam Nevler, Atrayee Basu Mallick, Rajan K. Singla, Peter A. McCue, Wilbur B. Bowne and Wei Jiang
    Citation: Diagnostic Pathology 2023 18:45
  23. Low-grade papillary Schneiderian carcinoma (LGPSC) is a relatively new entity of the sinonasal tract and is characterized by a bland morphology simulating sinonasal papilloma, invasive growth pattern with push...

    Authors: Sayaka Yuzawa, Tomohiko Michizuka, Rika Kakisaka, Yusuke Ono, Manami Hayashi, Miki Takahara, Akihiro Katada, Yusuke Mizukami and Mishie Tanino
    Citation: Diagnostic Pathology 2023 18:44
  24. PTEN hamartoma tumour syndrome (PHTS) is a rare hereditary disorder caused by germline pathogenic mutations in the PTEN gene. This study presents a case of PHTS referred for genetic evaluation due to multiple pol...

    Authors: Zahra Rahmatinejad, Ladan Goshayeshi, Robert Bergquist, Lena Goshayeshi, Amin Golabpour and Benyamin Hoseini
    Citation: Diagnostic Pathology 2023 18:43
  25. Splenogonadal fusion (SGF) is a rare congenital malformation in which the spleen is abnormally connected to the gonads or to the mesonephric derivatives. There is no obvious causality between SGF and testicula...

    Authors: Donglai Shen, Yuzhu Li, Yu Zhang, Xiao Chang, Xupeng Zhao, Jiabin Li, Xu Zhang and Gang Guo
    Citation: Diagnostic Pathology 2023 18:42
  26. Epithelioid and spindle rhabdomyosarcoma (ES-RMS) with TFCP2 rearrangement is a recently discovered rare variant of rhabdomyosarcoma composed of epithelioid and spindle cells, because it shows extraordinarily ...

    Authors: Yuan Li, Dan Li, Jingyu Wang and Jinlong Tang
    Citation: Diagnostic Pathology 2023 18:41
  27. Complete and partial moles (PM) are the most common gestational trophoblastic diseases. Due to some overlapping morphological findings, ancillary studies may be necessary.

    Authors: Behnaz Jahanbin, Soheila Sarmadi, Dorsa Ghasemi, Fatemeh Nili, Jafar-Ali Moradi and Soha Ghasemi
    Citation: Diagnostic Pathology 2023 18:40
  28. Authors: Xiang Li, Hongxia Zhang, Yong Cui, Haijun Zhang, Yonggang Wang, Meili Ding, Xingyao Zhu, Ruiqi Zhang, Qi Hu, Lin Tao, Wenhao Hu, Xinxia Li, Qilin AO and Hong Zou
    Citation: Diagnostic Pathology 2023 18:38

    The original article was published in Diagnostic Pathology 2023 18:35

  29. Clear cell Renal cell carcinoma (ccRCC) is an immunogenic tumor. B7 family members, such as CTLA-4, PD-1, and PD-L1, are the main components of immune checkpoints that regulate various immune responses. Specif...

    Authors: Jung Hee Lee, Yong Jun Kim, Hyun Woo Ryu, Seung Won Shin, Eun Ji Kim, So Hyun Shin, Joon Young Park, So Young Kim, Chung Su Hwang, Joo-Young Na, Dong Hoon Shin, Jee Yeon Kim and Hyun Jung Lee
    Citation: Diagnostic Pathology 2023 18:36

    The Correction to this article has been published in Diagnostic Pathology 2023 18:63

  30. Myeloid Sarcoma with monocytic differentiation is rare and quite likely is missed by surgical pathologists. However it is frequently misdiagnosed because of its non-specific imaging and histological pattern.

    Authors: Xiang Li, Hongxia Zhang, Yong Cui, Haijun Zhang, Yonggang Wang, Meili Ding, Xingyao Zhu, Ruiqi Zhang, Qi Hu, Lin Tao, Wenhao Hu, Xinxia Li, Qilin AO and Hong Zou
    Citation: Diagnostic Pathology 2023 18:35

    The Correction to this article has been published in Diagnostic Pathology 2023 18:38

  31. The ZC3H7B-BCOR fusion gene has recently been described in tumours with kinship to so-called high grade endometrial stromal sarcoma (HG-ESS). This subset of tumour behaves similarly to YWHAE-NUTM2A/B HG-ESS, howe...

    Authors: Ashlyn Fong and Saul Offman
    Citation: Diagnostic Pathology 2023 18:34
  32. Lung adenocarcinoma (LUAD) is a prevalent malignancy. SNHG15 has been demonstrated to be oncogenic in many kinds of cancers, however the mechanism of SNHG15 in LUAD cisplatin (DDP) resistance remains unclear. ...

    Authors: Yong Li, Hui-Qin Huang, Zheng-Hui Huang, Nan-Ding Yu, Xiang-Li Ye, Mei-Chen Jiang and Li-Min Chen
    Citation: Diagnostic Pathology 2023 18:33
  33. We examined a large cohort of serous tubo-ovarian tumors with 26 immunohistochemical markers, with the aim to assess their value for differential diagnosis and prognosis.

    Authors: Kristýna Němejcová, Adam Šafanda, Michaela Kendall Bártů, Romana Michálková, Jana Drozenová, Pavel Fabian, Jitka Hausnerová, Jan Laco, Radoslav Matěj, Gábor Méhes, Petr Škapa, Ivana Stružinská and Pavel Dundr
    Citation: Diagnostic Pathology 2023 18:32
  34. Carotid body tumors (CBTs) are rare neuroendocrine neoplasms arising near the carotid bifurcation with a reported incidence of 1 to 2 cases in 100,000 patients. Most CBTs are sporadic, benign, slow-growing, an...

    Authors: Jazmyne N. Tabb, Jared A. Maas, Bhargav P. Earla, Kenneth B. Fallon, Andrew M. McDonald and Michael C. Dobelbower
    Citation: Diagnostic Pathology 2023 18:31
  35. Eosinophilic angiocentric fibrosis (EAF) is a rare inflammatory lesion, especially in orbit. EAF is believed to be related to IgG4-related disease (IgG4-RD), but the clinical manifestations of systemic involve...

    Authors: Rui Liu, Jing Li, Tingting Ren, Hong Zhang and Jianmin Ma
    Citation: Diagnostic Pathology 2023 18:30
  36. Liver cirrhosis patients are at risk for esophagogastric variceal bleeding (EGVB). Herein, we aimed to estimate the EGVB risk in patients with liver cirrhosis using an artificial neural network (ANN).

    Authors: Yixin Hou, Hao Yu, Qun Zhang, Yuying Yang, Xiaoli Liu, Xianbo Wang and Yuyong Jiang
    Citation: Diagnostic Pathology 2023 18:29
  37. Epstein-Barr virus (EBV) infection may present with fulminant constitutional symptoms, cytopenia(s), and systemic lymphadenopathy, raising clinical suspicion for lymphoma and prompting lymph node and bone marr...

    Authors: Bradley Zehr, Kristina Brannock, Rebecca Wyma and Samir B. Kahwash
    Citation: Diagnostic Pathology 2023 18:28
  38. For clear cell renal cell carcinoma (ccRCC) with cystic component similar to multilocular cystic renal neoplasm of low malignant potential (MCRN-LMP) and solid low-grade component simultaneously, we propose th...

    Authors: Bo Yang, Lin Sun, Wen-feng Cao, Li-sha Qi, Yu-hong Guo and Yan Sun
    Citation: Diagnostic Pathology 2023 18:27
  39. Gastroblastoma is a rare gastric tumor composed of epithelial and spindle cell components. The characteristic MALAT–GLI1 fusion gene has only been identified in 5 reported cases. We report the morphological chara...

    Authors: Ryo Sugimoto, Noriyuki Uesugi, Noriyuki Yamada, Mitsumasa Osakabe, Shigeaki Baba, Naoki Yanagawa, Yuji Akiyama, Wataru Habano, Akira Sasaki, Yoshinao Oda and Tamotsu Sugai
    Citation: Diagnostic Pathology 2023 18:24
  40. The precise grading and characterization of cervical intraepithelial neoplasia (CIN) has been the focus of pathologists for a long time. This study aimed to explore known strategies for the grading of CINs.

    Authors: Ruichao Chen, Renchao Zhang, Minfen Zhang, Shaoyan Liu, Mingyu Xie, Zhongfeng Yang, Quan Shi, Hui Chen, Hanzhen Xiong, Na Wang and Qingping Jiang
    Citation: Diagnostic Pathology 2023 18:23
  41. Rosai-Dorfman disease (RDD) is a rare, non-Langerhans cell histiocytosis of unknown etiology. we report a very rare case of recurrent central nervous system RDD with KRAS gene mutation and review the literatur...

    Authors: Qingyang Wang, Hongxiang Ren, Liyuan Zheng, Juan Wang and Dingrong Zhong
    Citation: Diagnostic Pathology 2023 18:21
  42. Liver tumors exhibiting hepatocellular, cholangiocarcinoma, and neuroendocrine features are extremely rare, with only five cases reported in the literature.

    Authors: Alyeesha B. Wilhelm, Arwyn G. Cunningham, Cynthia Kassab, Eric C. Fitz, Jianli Dong, Ravi S. Radhakrishnan, Sarangarajan Ranganathan, Dongfeng Tan and Heather L. Stevenson
    Citation: Diagnostic Pathology 2023 18:20

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