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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. Current diagnostic criteria of adrenocortical neoplasms are mostly based on morphology. The utility of immunohistochemistry (IHC) and histochemistry is limited.

    Authors: Wenting Gan, Xue Han, Yuxi Gong, Yefan Yang, Cong Wang and Zhihong Zhang
    Citation: Diagnostic Pathology 2024 19:71
  2. IDH1 and IDH2 mutational status is a critical biomarker with diagnostic, prognostic, and treatment implications in glioma. Although IDH1 p.R132H-specific immunohistochemistry is available, it is unable to identif...

    Authors: James P. Solomon, Carlos Munoz-Zuluaga, Cheyanne Slocum, Alicia Dillard, Lin Cong, Jiajing Wang, Neal Lindeman, Michael Kluk, Benjamin Liechty, David Pisapia, Hanna Rennert and Priya D. Velu
    Citation: Diagnostic Pathology 2024 19:70
  3. Primary malignant hepatic vascular tumors with various malignant potentials include epithelioid hemangioendothelioma (EHE) and angiosarcoma (AS), which may overlap pathologically. This study aimed to compare t...

    Authors: Youngeun Yoo, Jinho Shin, Eunsung Jun, Eun-Young Koh, Hwa Jeong Shin and Hyo Jeong Kang
    Citation: Diagnostic Pathology 2024 19:68
  4. Prostate cancer is the leading cause of cancer-related death and the second most commonly diagnosed cancer among men in Uganda and most countries in Sub-Saharan Africa (SSA). The TMPRSS2-ERG fusion gene is the...

    Authors: Yekosani Mitala, Brian Ssenkumba, Abraham Birungi, Ritah Kiconco, Marvin Mwesigwa Mutakooha and Raymond Atwine
    Citation: Diagnostic Pathology 2024 19:67
  5. TFEB/6p21/VEGFA-amplified renal cell carcinoma (RCC) is rare and difficult to diagnose, with diverse histological patterns and immunohistochemical and poorly defined molecular genetic characteristics.

    Authors: Ruiqi Zhang, Meili Ding, Xingyao Zhu, Xiang Li, Qi Hu, Lin Tao, Wenhao Hu and Hong Zou
    Citation: Diagnostic Pathology 2024 19:66
  6. MEIS1::NCOA2 is a rare fusion gene that has been recently described in a subset of spindle cell rhabdomyosarcomas and multiple low-grade undifferentiated spindle cell sarcomas predominantly arising in the genitou...

    Authors: Zachary Coty-Fattal, Bianca Carter, Michael J. Volek and Farres Obeidin
    Citation: Diagnostic Pathology 2024 19:65
  7. A rare case of neuroendocrine cell tumor (NET) having both conventional and mucinous components was reported. Mucinous NET is rarely encountered in the pathological diagnosis of gastrointestinal (GI) tumors. H...

    Authors: Tamotus Sugai, Noriyuki Uesugi, Masamichi Suzuki, Nobuyasu Suzuki, Michitaka Honda, Tsuyoshi Abe and Naoki Yanagawa
    Citation: Diagnostic Pathology 2024 19:64
  8. Squamous cell carcinoma (SCC) of the dorsum of the tongue is extremely rare, and it clinically resembles various benign lesions. Somatic mutations in TP53 and some driver genes were implicated in the development ...

    Authors: Sawako Ono, Katsutoshi Hirose, Shintaro Sukegawa, Kyoichi Obata, Masanori Masui, Kazuaki Hasegawa, Ai Fujimura, Katsumitsu Shimada, Satoko Nakamura, Akari Teramoto, Yumiko Hori, Eiichi Morii, Daisuke Motooka, Takuro Igawa, Takehiro Tanaka, Hitoshi Nagatsuka…
    Citation: Diagnostic Pathology 2024 19:63
  9. Alveolar soft part sarcoma is a rare tumour of soft tissues, mostly localized in muscles or deep soft tissues of the extremities. In rare occasions, this tumour develops in deep tissues of the abdomen or pelvis.

    Authors: René Guérin, Anne-Lise Menard, Emilie Angot, Nicolas Piton, Pierre Vera, Lilian Schwarz, Jean-Christophe Sabourin, Marick Laé and Pierre-Alain Thiébaut
    Citation: Diagnostic Pathology 2024 19:62
  10. EBUS-TBNA has emerged as an important minimally invasive procedure for the diagnosis and staging of lung cancer. Our objective was to evaluate the effect of different specimen preparation from aspirates on the...

    Authors: Hansheng Wang, Jiankun Wang, Yan Liu, Yunyun Wang, Yanhui Zhou, Dan Yu, Hui You, Tao Ren, Yijun Tang and Meifang Wang
    Citation: Diagnostic Pathology 2024 19:61
  11. MNDA (myeloid nuclear differentiation antigen) has been considered as a potential diagnostic marker for marginal zone lymphoma (MZL), but its utility in distinguishing MZL from other B-cell non-Hodgkin lymphom...

    Authors: Li-Fen Zhang, Yan Zhang, Rou-Hong Shui, Hong-Fen Lu, Wen-Hua Jiang, Xu Cai, Xiao-Qiu Li and Bao-Hua Yu
    Citation: Diagnostic Pathology 2024 19:60
  12. PEComa is a mesenchymal tumor that can occur in various organs including the uterus and soft tissues. PEComas are composed of perivascular epithelioid cells, and angiomyolipoma (AML), clear cell sugar tumor (C...

    Authors: Hikaru Tsukita, Kei Koyama, Takahiro Ishinari, Ayana Takahashi, Ken Miyabe, Michinobu Umakoshi, Makoto Yoshida, Yukitsugu Kudo-Asabe, Akiko Nishida, Naohiko Otsuka, Ouki Yasui, Ikuma Kato, Noriyoshi Fukushima and Akiteru Goto
    Citation: Diagnostic Pathology 2024 19:59
  13. Crizotinib, an oral first-generation tyrosine kinase inhibitor (TKI), is superior to systemic chemotherapy for the treatment of non-small cell lung cancer (NSCLC) with positive rearrangement of anaplastic lymp...

    Authors: Peng Zhang, JiaHua Xu, Qing Wu, Jianxin Qian and Song Wang
    Citation: Diagnostic Pathology 2024 19:58
  14. Cementoblastoma is a rare odontogenic tumor characterized by the formation of osteocementum-like tissue on a tooth root directly by neoplastic cementoblasts. Although it is categorized as benign, it has a high...

    Authors: Kaori Oya, Akinori Takeshita, Kanta Wakamori, Misa Song, Hayato Kimura, Katsutoshi Hirose, Hiroaki Shimamoto, Sunao Sato, Kazuhide Matsunaga, Narikazu Uzawa and Satoru Toyosawa
    Citation: Diagnostic Pathology 2024 19:57
  15. Colorectal cancer (CRC) frequently involves mutations in the KRAS gene, impacting therapeutic strategies and prognosis. The occurrence of KRAS mutations typically precludes the presence of RET fusions, with curre...

    Authors: Tillmann Bedau, Carina Heydt, Udo Siebolts, Thomas Zander, Max Kraemer, Heike Loeser, Reinhard Buettner and Alexander Quaas
    Citation: Diagnostic Pathology 2024 19:55
  16. Melanocytic lesions involving the central nervous system are extremely rare and pose a diagnostic challenge owing melanoma being the third most common malignancy metastasizing to the spine. Morphology and immu...

    Authors: Raghav Kapoor, Anurag Mehta, Anila Sharma, Shrinidhi Nathany, Himanshi Diwan and Divya Bansal
    Citation: Diagnostic Pathology 2024 19:54
  17. Accurately predicting the response to neoadjuvant chemotherapy (NAC) in breast cancer patients is crucial for guiding treatment strategies and enhancing clinical outcomes. Current studies have primarily focuse...

    Authors: Mijia Wang, Zhendong Wei, Jixia Kong and Haidong Zhao
    Citation: Diagnostic Pathology 2024 19:53
  18. Papillary carcinoma is the most frequent type of thyroid carcinoma, while primary thyroid lymphoma is uncommon disease. The coexistence of these entities has already been described, and the common risk factor ...

    Authors: Igor Iskra, Maja Ilić Tomaš, Tatjana Bogović Crnčić, Edvin Kukić, Ita Hadžisejdić, Manuela Avirović and Neva Girotto
    Citation: Diagnostic Pathology 2024 19:52
  19. Oral squamous cell carcinoma in minors is considered to be a distinct entity from OSCC in older patients, with an uncertain etiology. Human papillomavirus (HPV) infection may trigger the initiation and promote...

    Authors: Ningxiang Wu, Yonghui Li, Xiaokun Ma, Zhen Huang, Zhuoxuan Chen, Weihua Chen and Ran Zhang
    Citation: Diagnostic Pathology 2024 19:51
  20. Patients with hypopharyngeal carcinoma (HPC) have a poor prognosis mainly because of lymphatic metastasis. This research aimed to determine the PKM2 role in lymphatic metastasis in HPC and the underlying molec...

    Authors: Xin Zhou, Yanshi Li, Min Pan, Tao Lu, Chuan Liu, Zhihai Wang, Fengxiang Tang and Guohua Hu
    Citation: Diagnostic Pathology 2024 19:48
  21. Amyotrophic lateral sclerosis (ALS) is a progressive and fatal motor neuron disease. Due to the limited knowledge about potential biomarkers that help in early diagnosis and monitoring disease progression, tod...

    Authors: Shahram Darabi, Armin Ariaei, Auob Rustamzadeh, Dariush Afshari, Enam Alhagh Charkhat Gorgich and Leila Darabi
    Citation: Diagnostic Pathology 2024 19:47
  22. Primary mucoepidermoid carcinomas (MECs) of the sinonasal tract and nasopharynx are rare entities that represent a diagnostic challenge, especially in biopsy samples. Herein, we present a case series of MECs o...

    Authors: Chunyan Hu, Lan Lin, Ming Ye, Yifeng Liu, Qiang Huang, Cuncun Yuan, Ji Sun and Hui Sun
    Citation: Diagnostic Pathology 2024 19:46
  23. Fungal infection incidental detection is a common encounter in cytopathology practices. Detection of the fungal organisms and awareness of the morphological features are challenges for the cytopathologist.

    Authors: Tummidi Santosh, Indranil Chakrabarti, Aparna Palit and Sonakshi Srivastava
    Citation: Diagnostic Pathology 2024 19:45
  24. Lymph node ratio (LNR) may offer superior prognostic stratification in colorectal adenocarcinoma compared with N stage. However, candidate cutoff ratios require validation. We aimed to study the prognostic sig...

    Authors: Amir F. Beirat, Justin Z. Amarin, Haya H. Suradi, Yasmeen Z. Qwaider, Adel Muhanna, Bayan Maraqa, Abdallah Al-Ani and Maysa Al-Hussaini
    Citation: Diagnostic Pathology 2024 19:44
  25. The integration of large language models (LLMs) like ChatGPT in diagnostic medicine, with a focus on digital pathology, has garnered significant attention. However, understanding the challenges and barriers as...

    Authors: Ehsan Ullah, Anil Parwani, Mirza Mansoor Baig and Rajendra Singh
    Citation: Diagnostic Pathology 2024 19:43
  26. Staining tissue samples to visualise cellular detail and tissue structure is at the core of pathology diagnosis, but variations in staining can result in significantly different appearances of the tissue sampl...

    Authors: Catriona Dunn, David Brettle, Martin Cockroft, Elizabeth Keating, Craig Revie and Darren Treanor
    Citation: Diagnostic Pathology 2024 19:42
  27. Dermatofibrosarcoma protuberans (DFSP) is a low-grade malignant soft-tissue tumor that originates from the skin. It has a slow onset in the early stages, non-specific clinical symptoms, low specificity, and ca...

    Authors: Minying Deng, Qingxiao Liu, Lei Ren, Wei Yuan, Chen Xu and Yingyong Hou
    Citation: Diagnostic Pathology 2024 19:41
  28. Fat-forming solitary fibrous tumor is a rare and specific subtype of solitary fibrous tumor. In this case, a mass of 8.3 cm in diameter was found in a 59-year-old male patient’s right retroperitoneum, as revea...

    Authors: Yi-Dan Ma, Zi-Qing Wu, Xin-Rong Liang, Lin Jing Pi, Meng-Zhen Gong and Yao Tang
    Citation: Diagnostic Pathology 2024 19:40
  29. Caroli’s syndrome is a congenital disease characterized by dilation of intrahepatic bile ducts and congenital hepatic fibrosis. It is a rare condition in clinical work. Typically, the diagnosis of this disease...

    Authors: Tianmin Zhou, Keyu Liu, Hao Wei, Qingmei Zhong, Daya Luo, Wenjuan Yang, Ping Zhang and Yingqun Xiao
    Citation: Diagnostic Pathology 2024 19:36
  30. Breast cancer is one of the most common diseases worldwide that affects women of reproductive age. miR-221 and miR-222 are two highly homogeneous microRNAs that play pivotal roles in many cellular processes and r...

    Authors: Touba Eslaminejad, Seyed Noureddin Nematollahi-Mahani, Marzieh Lotfian Sargazi, Mehdi Ansari and Vida Mirzaie
    Citation: Diagnostic Pathology 2024 19:35
  31. Epstein-Barr virus-positive inflammatory follicular dendritic cell sarcoma (EBV+IFDCS) is a rare disease characterized by mild clinical symptoms and non-specific imaging findings. The diagnosis of the disease ...

    Authors: Chenchen Nie, Xun Xie, Hangyan Li, Yangcan Li, Zhihong Chen, Yanchun Li and Zhenfeng Li
    Citation: Diagnostic Pathology 2024 19:34
  32. Hypercytokinemia, the renin-angiotensin system, hypoxia, immune dysregulation, and vasculopathy with evidence of immune-related damage are implicated in brain morbidity in COVID-19 along with a wide variety of...

    Authors: Roy H. Rhodes, Gordon L. Love, Fernanda Da Silva Lameira, Maryam Sadough Shahmirzadi, Sharon E. Fox and Richard S. Vander Heide
    Citation: Diagnostic Pathology 2024 19:33
  33. Accurate quantification of human epidermal growth factor receptor 2 (HER2) gene amplification is important for predicting treatment response and prognosis in patients with breast cancer. Fluorescence in situ hybr...

    Authors: Vicente Peg, Teresa Moline, Miquel Roig, Yuko Saruta and Santiago Ramon y Cajal
    Citation: Diagnostic Pathology 2024 19:32
  34. This letter concerns retracted papers published in the Journal of Diagnostic Pathology, where my name was misused as the author or corresponding author without my permission or knowledge. Considering that all ...

    Authors: Aram Mokarizadeh
    Citation: Diagnostic Pathology 2024 19:31
  35. Cytotoxic lymphocytes (CLs) express potent toxins, including perforin (P) and granzyme-B (G), which brings about target cell death. The purpose of this study was to evaluate the killing capacity of tumor-infil...

    Authors: Xiaogang Liu, Honggang Liu, Lu Wang, Yubing Han, Linghong Kong and Xinpeng Zhang
    Citation: Diagnostic Pathology 2024 19:29
  36. Benign nerve sheath tumors (BNSTs) present diagnostic challenges due to their heterogeneous nature. This study aimed to determine the significance of NRG1 as a novel diagnostic biomarker in BNST, emphasizing i...

    Authors: Suwei Yan, Jingnan Zhao, Pengyang Gao, Zhaoxu Li, Zhao Li, Xiaobing Liu and Pengfei Wang
    Citation: Diagnostic Pathology 2024 19:28
  37. NUT carcinoma is a rare cancer associated with a poor prognosis. Because of its rarity, its diagnosis is challenging and is usually made by excluding other diagnoses. Immunohistochemical analysis is a reliable...

    Authors: Hironori Ninomiya, Yukiko Sato, Kentaro Inamura, Akito Dobashi, Kengo Takeuchi, Hiroki Mitani, Mingyon Mun, Makoto Nishio and Yuichi Ishikawa
    Citation: Diagnostic Pathology 2024 19:27
  38. Differences in the preparation, staining and scanning of digital pathology slides create significant pre-analytic variability. Algorithm-assisted tools must be able to contend with this variability in order to...

    Authors: Ariel Greenberg, Benzion Samueli, Shai Farkash, Yaniv Zohar, Shahar Ish-Shalom, Rami R. Hagege and Dov Hershkovitz
    Citation: Diagnostic Pathology 2024 19:26
  39. Multiple primary malignancies are rare in cancer patients, and risk factors may include genetics, viral infection, smoking, radiation, and other environmental factors. Lynch syndrome (LS) is the most prevalent...

    Authors: Tiansong Zhang, Xiaoqiang Huang, Wenjie Liu, Xiulan Ling, Zhenping Su, Mengwei Huang and Shuanlong Che
    Citation: Diagnostic Pathology 2024 19:25
  40. Follicular dendritic cell sarcoma (FDCS) is a rare low-grade tumor of the lymph nodes, but roughly one-third of the cases emerge from extranodal sites, posing diagnostic challenges.

    Authors: Tamás Pancsa, Borbála Dénes, Áron Somorácz, Dóra Kelemen, Ferenc Salamon, Fanni Sánta and Levente Kuthi
    Citation: Diagnostic Pathology 2024 19:24

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