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Table 1 Previously reported cases of morphologically pure adenoid basal lesions in the English literature.

From: Adenoid basal lesions of the uterine cervix: evolving terminology and clinicopathological concepts

  Authors (reference) No of patients age (yrs) Race Presentation/pap smear findings Gross or pelvic examination findings Associated cervical intraepithelial dysplastic lesion Diagnostic and/or Therapeutic measure(s) Lymph node status Follow-up, (months)
1 Baggish & Woodruff [24]*** 1 63 white Vaginal bleeding/NR Atrophic vaginal mucosa; NCF CIS Hysterectomy/BSO NPR NED 156
2   1 62 black Uterine prolapse/NR NCF CIS Hysterectomy NPR NED 84
3   1 39 black Abnormal pap smear NR CIS Conization/Hysterectomy NPR NED 60
4 Baggish & Woodruff [23] 1 60 white "incidental"/negative NCF None Hysterectomy/BSO NPR NED 6
5 Cases 1–3 1 80 white "incidental"/negative NCF None Hysterectomy/BSO NPR NED 6
6   1 80 black Lower abdominal pressure/negative Cervical eversion CIS Conization/Hysterectomy/BSO NPR NED 6
7 Russell & Laverty [22] 1 62 NR uterine prolapse and vaginal bleeding/"Very Atypical cells" Cervical ulceration None Hysterectomy NPR NR
8 Daroca & Dhurandhar [25], Case 3 1 60 NR Post menopausal bleeding Cervical erosion CIS Hysterectomy/BSO NPR NED 12
9–13 van Dinh & Woodrhuff [21]## 5 mean 56 white 3, black 2 Vaginal bleeding n = 1, asymptomatic n = 4/moderate atypia n = 5 Cervical ulceration n = 1, NCF n = 4 CIN3 n = 3, None n = 2 dilatation and curettage n = 1, Hysterectomy +/- BSO n = 4 NPR DOC n = 1, NED 24–144, n = 4
14 Ferry & Scully [20] 1 69 black Abnormal pap smear n = 11, PMB n = 2 NCF n = 10, cervical induration n = 2, CIS Hysterectomy/BSO NPR NED 60
15 Cases 1–13 1 63 NR    CIS Hysterectomy/BSO NPR NED 120
16   1 66 black    CIS Cervical excision/Rad NPR DOC 24
17   1 75 white    CIS Hysterectomy/BSO NPR NED 84
18   1 65 asian    CIS Hysterectomy/BSO/Rad NPR NED 72
19   1 51 NR    CIS Hysterectomy/BSO NPR NED 24
20   1 56 NR    CIS Cervical excision NPR NED 72
21   1 78 white    CIS Cervical excision NPR NED 72
22   1 59 white    CIS Hysterectomy/RSO NPR NED 60
23   1 67 black    CIS Hysterectomy/BSO NPR NED 48
24   1 57 white    CIS Hysterectomy/BSO NPR NED 24
25   1 72 black    CIS Conization NPR NED 29
26   1 57 NR    CIS NR NPR DOC 0
27 Langlois et al [19] 1 59 NR Asymptomatic/abnormal pap smear NCF CIN3 Conization, Hysterectomy NPR NR
28 Peterson & Neumann [18] 1 64 other Asymptomatic/HGSIL NR CIN2 Conization NPR NR
29 Layton-Henry et al [17] 1 62 NR Abnormal Pap smear n = 5/HGSIL, one with "possible invasion", n = 3; inconclusive n = 2 NCF CIN Conization, Hysterectomy, BSO, LN Negative NED 1
30   1 64 NR   NCF CIN Conization, Hysterectomy, BSO NPR NED 7
31   1 75 NR   NCF CIN Conization NPR NED 15
32   1 60 NR   NCF CIN Conization, Hysterectomy, BSO, LN Negative NED 26
33   1 59 NR   NCF CIN Conization, Hysterectomy, BSO, LN Negative VAIN 16
34 Powers & Frable [16] 1 79 white Asymptomatic/SCC AWL CIS Conization, Hysterectomy BSO, LN Negative NED 18
35   1 67 black Presentation @/"severely atypical small cells" NCF None Conization, Rad NPR NED 16
36–40 Jones et al [13] 1 Mean 51 white n = 5 abnormal pap n = 4, PMB n = 1 "Ulcerated, irregular indurated mass" n = 2, NCF n = 3 CIN 1 to3 (n = 5) Hysterectomy/BSO (n = 5), Hysterectomy/BSO/LN (n = 4). One patient also received Rad Negative NED 26 Mean
41 Yoshida et al [14] 1 49 asian Asymptomatic NCF CIN 3 Hysterectomy NPR NR
42–45* Grayson et al [9] (Cases 4,5,7,8) 4 NI black NI NI NI NI NI NI
46 Brainard & Hart [10] 1 91 NR Dysuria, Night sweats/HGSIL Focal hemorrhage CIS Conization NPR NED 4
47   1 68 NR Asymptomatic/HGSIL NCF CIS Conization, Hysterectomy, BSO, LN Negative NED 5
48   1 78 NR Vaginal spotting/HGSIL NCF Severe dysplasia Conization, Hysterectomy, BSO, LN Negative NED 15
49   1 30 NR Asymptomatic/HGSIL NCF Moderate severe dysplasia Conization, Hysterectomy, BSO, LN Negative NED 17
50   1 71 NR Asymptomatic/HGSIL NCF CIS Conization NPR NED 21
51   1 67 NR Asymptomatic/HGSIL NCF Microinvasive Carcinoma## Conization, Hysterectomy, BSO, LN Negative NED 28
52   1 70 NR Dysuria, Hematuria/Negative NCF None Hysterectomy NPR NED 30
53   1 72 NR Asymptomatic/HGSIL NCF CIS Conization, Hysterectomy NPR NED 70
54   1 71 NR Asymptomatic/HGSIL NCF CIS Conization, BSO, Rad, LN Negative NED 82
55   1 76 NR NR/HGSIL NCF CIS Hysterectomy, BSO NPR NED 24
56   1 70 NR Asymptomatic/LGSIL NCF CIS Hysterectomy, Rad NPR NED 63
57   1 83 NR Asymptomatic/HGSIL NCF CIS Conization NPR NED 87
58   1 35 NR Pelvic mass@/Normal NCF None Hysterectomy, BSO, LN, Chemotherapy [all@] Negative NED 49
59   1 57 NR Asymptomatic/CIS NCF CIN Conization NPR NED 5
60   1 69 NR Asymptomatic/abnormal pap smear NCF None Conization NPR NR
61 Senzaki et al [11] 1 69 asian Vaginal bleeding NCF CIS Hysterectomy, BSO, LN [all@] Negative NED 6
62 Hiroi et al [6] 1 74 asian Vaginal bleeding NCF CIN 3 Hysterectomy NPR NR
63 Khoury et al [4] 1 79 black Asymptomatic/HGSIL NCF Severe dysplasia Hysterectomy, BSO NPR NR
64 Teramoto [2] 1 69 asian Asymptomatic/HGSIL NR CIN3 Hysterectomy and chemotherapy@ NPR 108
65 Zamecnik & Skrivanek [1] 1 21 NR Asymptomatic//LGSIL NCF CIN1-3 Conization NPR NED 1
66 Parwani et al [1] 1 65 NR NR/HGSIL NR Microinvasive Carcinoma## Conization, Hysterectomy, LN Negative NED 78
  1. Abbreviations: NED, no evidence of disease; CIS, carcinoma in situ; LN, lymph node dissection; N/A, not applicable; PMB postmenopausal bleeding; BSO or RSO bilateral or right salpingo-oophorectomy; Rad, radiation therapy; NPR Lymph node dissection not performed or reported; NCF no gross cervical findings; DOC death from other causes; LGSIL low grade squamous intraepithelial lesion; HGSIL high grade squamous intraepithelial lesion; CIN cervical intraepithelial neoplasia. Cases in Cviko et al [8] are excluded due to lack of sufficient clincopathological information; SCC squamous cell carcinoma. **Presumes cases in Grayson et al (1997) are the same in Grayson et al (1999); AWL: acetowhite lesions. NI: information not included due to a lack of sufficient itemization in original manuscript. NA: information not available. *excludes the 4 cases in Grayson et al [9] with "divergent neoplastic epithelial differentiation"; *** follow-up as reported in [23]; @ Unrelated to cervical pathology; ## Includes the cases of microinvasive carcinoma [1,10,20], see text