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Table 2 Pathologic characteristics of primary testicular angiosarcoma

From: Primary angiosarcoma of the testis: report of a rare entity and review of the literature

Source, year Macroscopic findings of angiosarcoma     
  Gross Site Size, cm Architectural patterns of angiosarcoma Cytologic features Mitotic rate Immuno-phenotype
Hughes et al, 1991 [1] *Flesh-colored intervening stroma Testicular parenchyma 9 * Classic Typical NA FVII+, UEL+
Masera et al, 1999 [2] Well-vascularised lesion Testicular parenchyma 1.7 Classic Epithelioid High FVIII+, UEL+, CD31+, CD34+, Pancytokeratin-, CD68-, LCA-, PLAP-
Steele et al, 2000 [3] *Vascular solid mass Testicular parenchyma with invasion of rete testis, epididymis, and spermatic cord 8 *Classic Epithelioid NA FVIII+, CD31+
Sahoo et al, 2003 [4] #Vascular solid mass #Retroperitoneum 10 #Classic, focally solid Epithelioid and spindled NA CD31+, CD34+, AE1/AE3-, CAM5.2-, PLAP-
Current case Solid vascular nodule Testicular parenchyma with invasion of epididymis 3 Classic, focally solid Typical 8/10 HPF UEL+, CD31+, CD34+, AE1/AE3-, Pancytokeratin-
  1. NA: not available; FVIII, factor VIII-related antigen; UEL, Ulex europaeus lectin, LCA, leucocyte common antigen; PLAP, placental alkaline phosphatase.
  2. *Concurrent presence of multiloculated cystic areas diagnosed as mature teratoma in the same testicular tumor.
  3. #Concurrent presence of multiloculated cystic testicular tumor diagnosed as mature teratoma.