Table 1 Comparison of key histologic features to the mentioned differential diagnosis
Histologic features | Fibroma with minor sex cord elements | Ovarian Fibromatosis | Brenner tumor | Adenofibroma |
|---|---|---|---|---|
Spindled cells in fascicles & whorls | Present | Present | Present | Present |
Collagen | Variable | Abundant | variable | variable |
Normal ovarian follicles | Replaced by fibrous stroma | Preserved | absent | absent |
Small nests of undifferentiated sex cord type cells | Present (<10% of tumor area) | absent | absent | absent |
Edema | absent | Present | absent | absent |
Epithelial nests of transitional/mucinous cells | absent | absent | Present | absent |