Table 1 Immunohistochemical findings of case of Xp11.2 translocation renal cell carcinoma with a novel translocation involving chromosome 19
Antibody to | Result (Positive, Negative) | Intensity (Strong, Moderate, Weak) | Immunoreactivity (1+, 2+, 3+) | Staining Pattern (Nuclear, Cytoplasmic) |
|---|---|---|---|---|
TFE3 | Positive | Strong | 3+ | Nuclear |
Cytokeratin AE1-AE3 | Positive | Moderate | 2+ | Cytoplasmic |
Cytokeratin CAM-5.2 | Positive | Moderate | 2+ | Cytoplasmic |
Cytokeratin 7 | Positive | Weak | 1+ | Cytoplasmic |
Epithelial membrane antigen | Positive | Strong | 3+ | Cytoplasmic |
Renal cell carcinoma antigen | Positive | Weak | 1+ | Cytoplasmic |
CD 10 | Positive | Strong | 3+ | Cytoplasmic |
E-cadherin | Positive | Strong | 3+ | Cytoplasmic |
Calveolin | Positive | Moderate | 2+ | Cytoplasmic |
Parvalbumin | Positive | Moderate | 2+ | Cytoplasmic |
Colloidal iron | Positive | Weak | 1+ | Cytoplasmic |
BerEP4 | Negative | Not Applicable | Not Applicable | Not Applicable |
Carbonic anhydrase IX | Negative | Not Applicable | Not Applicable | Not Applicable |