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Table 1 Sensitivity, specificity, and positive (PPV) and negative predictive value (NPV) for cytology, ImmunoCyt/uCyt+, CK20 and combinations.

From: Which urine marker test provides more diagnostic value in conjunction with standard cytology- ImmunoCyt/uCyt+ or Cytokeratin 20 expression

  

BiOPSY

RESULT

  

TEST

RESULT

  
  

LGUC

n = 31

HGUC

n = 23

Negative

Sensitivity

Specificity

PPV

NPV

OA

Cytology

+

21

20

12

75.9

66.7

77.3

88.9

72.2

 

-

10

3

24

     

UCyt+™

+

24

21

5

83.3

86.1

90.0

79.5

84.4

 

-

7

2

31

     
 

-

11

5

30

     

Cytology+ CK20

+

22

20

12

77.8

66.7

77.7

66.7

73.3

 

-

9

3

24

     

UCyt+™+ CK20

+

23

21

7

81.5

80.5

86.3

74.3

81.1

 

-

8

2

29

     
 

-

3

1

24

     
  1. +: Positive test result, -: Negative test result Negative: Negative for malignancy PPV:Positive predictive value NPV: Negative predictive value OA: Overall accuracy