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Table 1 Sensitivity, specificity, and positive (PPV) and negative predictive value (NPV) for cytology, ImmunoCyt/uCyt+, CK20 and combinations.

From: Which urine marker test provides more diagnostic value in conjunction with standard cytology- ImmunoCyt/uCyt+ or Cytokeratin 20 expression

   BiOPSY RESULT    TEST RESULT   
   LGUC n = 31 HGUC n = 23 Negative Sensitivity Specificity PPV NPV OA
Cytology + 21 20 12 75.9 66.7 77.3 88.9 72.2
  - 10 3 24      
UCyt+™ + 24 21 5 83.3 86.1 90.0 79.5 84.4
  - 7 2 31      
  - 11 5 30      
Cytology+ CK20 + 22 20 12 77.8 66.7 77.7 66.7 73.3
  - 9 3 24      
UCyt+™+ CK20 + 23 21 7 81.5 80.5 86.3 74.3 81.1
  - 8 2 29      
  - 3 1 24      
  1. +: Positive test result, -: Negative test result Negative: Negative for malignancy PPV:Positive predictive value NPV: Negative predictive value OA: Overall accuracy