| |
B7-H1
|
B7-H3
|
Survivin
|
Ki-67
|
CAIX*
|
IMP3
|
|---|
| |
Kappa
|
CCC
|
CCC
|
CCC
|
CCC
|
CCC
|
|---|
|
Whole section
|
0.78
|
0.97
|
0.71
|
0.90
|
0.94
|
0.96
|
|---|
|
Cores
| | | | | | |
|---|
|
1
|
0.21 (0.00 - 0.65)
|
0.80 (0.73 - 0.87)
|
0.35 (0.06 - 0.55)
|
0.63 (0.44 - 0.82)
|
0.85 (0.73 - 0.94)
|
0.73 (0.02 - 0.87)
|
|
2
|
0.21 (0.00 - 0.65)
|
0.81 (0.74 - 0.87)
|
0.40 (0.12 - 0.57)
|
0.72 (0.49 - 0.84)
|
0.82 (0.73 - 0.92)
|
0.79 (0.20 - 0.85)
|
|
3
|
0.38 (0.00 - 0.65)
|
0.83 (0.76 - 0.86)
|
0.43 (0.24 - 0.62)
|
0.76 (0.62 - 0.86)
|
0.80 (0.72 - 0.89)
|
0.81 (0.49 - 0.85)
|
|
4
|
0.38 (0.00 - 0.65)
|
0.83 (0.77 - 0.85)
|
0.44 (0.33 - 0.58)
|
0.79 (0.64 - 0.85)
|
0.78 (0.71 - 0.87)
|
0.82 (0.61 - 0.85)
|
|
5
|
0.52 (0.00 - 0.65)
|
0.83 (0.80 - 0.85)
|
0.45 (0.36 - 0.57)
|
0.81 (0.71 - 0.86)
|
0.77 (0.72 - 0.84)
|
0.82 (0.77 - 0.85)
|
|
6
|
0.52 (0.00 - 0.65)
|
0.84 (0.81 - 0.84)
|
0.45 (0.37 - 0.57)
|
0.81 (0.71 - 0.85)
|
0.76 (0.71 - 0.82)
|
0.82 (0.77 - 0.85)
|
|
7
|
0.65 (0.00 - 0.65)
|
0.84 (0.81 - 0.84)
|
0.46 (0.40 - 0.52)
|
0.82 (0.73 - 0.85)
|
0.75 (0.72 - 0.82)
|
0.82 (0.77 - 0.85)
|
|
8
|
0.65 (0.38 - 0.65)
|
0.84 (0.83 - 0.84)
|
0.46 (0.41 - 0.51)
|
0.82 (0.76 - 0.84)
|
0.74 (0.72 - 0.81)
|
0.82 (0.79 - 0.85)
|
|
9
|
0.65 (0.52 - 0.65)
|
0.84 (0.83 - 0.84)
|
0.46 (0.43 - 0.48)
|
0.82 (0.79 - 0.84)
|
0.73 (0.72 - 0.79)
|
0.82 (0.80 - 0.84)
|
|
10
|
0.65 (0.65 - 0.65)
|
0.84 (0.84 - 0.84)
|
0.46 (0.46 - 0.46)
|
0.82 (0.82 - 0.82)
|
0.73 (0.73 - 0.73)
|
0.82 (0.82 - 0.82)
|
- *CAIX was analyzed using the minimum value across cores. All other biomarkers were analyzed using the maximum value across cores.
- The kappa statistic is reported for B7-H1, whereas the concordance correlation coefficient (CCC) is reported for B7-H3, survivin, Ki-67, CAIX, and IMP3; the median (minimum, maximum) statistic from the 500 bootstrap samples is provided.
