| |
Acute (A) (≤8 hs) Median Expression
|
Non-acute (NA) (≥8 hs ≤48 hs) Median Expression
|
Controls (C) Median Expression
|
Significant Significance Level Levels
|
|---|
|
GFAP
|
+++
|
+++
|
+++
|
A vs C
|
ns
|
| | | | |
NA vs C
|
ns
|
| | | | |
A vs NA
|
ns
|
|
TNF-α
|
-
|
+
|
-
|
A vs C
|
***
|
| | | | |
NA vs C
|
ns
|
| | | | |
A vs NA
|
***
|
|
IL-1β
|
-
|
+
|
-
|
A vs C
|
***
|
| | | | |
NA vs C
|
ns
|
| | | | |
A vs NA
|
***
|
|
IL-6
|
-
|
++
|
-
|
A vs C
|
***
|
| | | | |
NA vs C
|
ns
|
| | | | |
A vs NA
|
***
|
|
MAC387
|
++
|
+
|
-
|
A vs C
|
***
|
| | | | |
NA vs C
|
***
|
| | | | |
A vs NA
|
**
|
|
HSP 27
|
-
|
-
|
-
|
A vs C
|
ns
|
| | | | |
NA vs C
|
ns
|
| | | | |
A vs NA
|
ns
|
|
HSP 70
|
+
|
++
|
-
|
A vs C
|
***
|
| | | | |
NA vs C
|
***
|
| | | | |
A vs NA
|
***
|
|
HSP 90
|
+
|
++
|
-
|
A vs C
|
***
|
| | | | |
NA vs C
|
***
|
| | | | |
A vs NA
|
***
|
|
COX2
| |
++
|
-
|
A vs C
|
***
|
| | | | |
NA vs C
|
ns
|
| | | | |
A vs NA
|
***
|
|
ORP-150
|
-
|
++
|
-
|
A vs C
|
***
|
| | | | |
NA vs C
|
ns
|
| | | | |
A vs NA
|
***
|
|
β-APP
|
+
|
++
|
++
|
A vs C
|
***
|
| | | | |
NA vs C
|
***
|
| | | | |
A vs NA
|
ns
|
|
TrypH
|
-
|
-
|
-
|
A vs C
|
ns
|
| | | | |
NA vs C
|
ns
|
| | | | |
A vs NA
|
ns
|
|
GAP-43
|
-
|
+
|
-
|
A vs C
|
***
|
| | | | |
NA vs C
|
ns
|
| | | | |
A vs NA
|
***
|
|
Apoptosis (TUNEL)
|
+
|
++
|
-
|
A vs C
|
***
|
| | | | |
NA vs C
|
***
|
| | | | |
A vs NA
|
***
|
- The reactions were graded as follows: 1. (0): not expressed, 2. (+): isolated and disseminated expression, 3. (++): expression in groups or widespread foci, 4. (+++): widespread expression.
- NS = p > 0.05, * = p < 0.05, ** = p < 0.01, *** = p < 0.001
