Figure 1

Immunohistochemical HER2 status of selected cases. A Correctly identified immunohistochemical HER2 status scored as 3+ (positive) which proved to be amplified by FISH. B False positive immunohistochemical HER2 status originally scored as 3+ which proved to be not amplified by FISH (Table 2, case 3). C False negative immunohistochemical HER2 status scored as 1+ which proved to be amplified by FISH (Table 2, case 4). D Immunohistochemical HER2 status scored as 1+ which proved to be equivocal by FISH (Table 2, case 5). A-D Dako clone A0485. ×20.