Table 2 MUC gene expression and logistic regression analysis of associations between MUC family genes and clinical characteristics
From: Mucins Differently Expressed in Various Ampullary Adenocarcinomas
| Â | MUC1 (n = 53) | MUC2 (n = 50) | MUC5AC (n = 51) | MUC6 (n = 48) |
|---|---|---|---|---|
Variable | No. (%) | |||
Gene Expression | Â | Â | Â | Â |
   Positive | 38 (71.7) | 10 (20.0) | 22 (43.1) | 13 (27.1) |
   Negative | 15 (28.3) | 40 (80.0) | 29 (56.9) | 35 (72.9) |
| Â | Â | OR (95% C.I.) | Â | Â |
Age | 1.02 (0.97, 1.07) | 1.01 (0.95, 1.07) | 1.07 (1.11, 1.14)* | 1.04 (0.97, 1.10) |
Gender | Â | Â | Â | Â |
   Female | 1.00 | 1.00 | 1.00 | 1.00 |
   Male | 2.45 (0.73, 8.42) | 2.96 (0.56, 15.73) | 0.88 (0.28, 2.74) | 2.22 (0.52, 9.54) |
Tumor size | 0.90 (0.50, 1.65) | 0.72 (0.32, 1.58) | 1.60 (0.86, 2.97) | 0.50 (0.22, 1.11) |
Location | Â | Â | Â | Â |
   Lower end of the common bile duct | 1.00 | 1.00 | 1.00 |  |
   Ampullary duodenum | 0.22 (0.02, 1.93) | - | 1.08 (0.13, 8.80) | - |
   Papillary duodenum | 0.35 (0.10, 1.31) | 1.25 (0.31, 5.09) | 0.58 (0.18, 1.91) | 1.50 (0.41, 5.51) |
Tumor differentiation | Â | Â | Â | Â |
   No & Low | 1.00 | 1.00 | 1.00 | 1.00 |
   Middle & High | 4.71 (1.26, 17.66)* | 0.91 (0.22, 3.62) | 1.55 (0.51, 4.74) | 0.47 (0.13, 1.72) |
Tumor classification | Â | Â | Â | Â |
   T0 & T1 & T2 | 1.00 | 1.00 | 1.00 | 1.00 |
   T3 & T4 | 1.50 (0.45, 5.05) | 0.43 (0.10, 1.90) | 2.05 (0.66, 6.31) | 1.56 (0.43, 5.59) |
Node classification | Â | Â | Â | Â |
   N0 | 1.00 | 1.00 | 1.00 | 1.00 |
   N1 | 1.09 (0.32, 3.69) | 1.00 (0.23, 4.11) | 1.90 (0.61, 5.90) | 0.36 (0.08, 1.52) |
Distant metastasis | Â | Â | Â | Â |
   M0 | 1.00 | 1.00 | 1.00 | 1.00 |
   M1 | 0.38 (0.02, 6.47) | - | 1.33 (0.80, 22.57) | - |
TNM stage | Â | Â | Â | Â |
   0 & I | 1.00 | 1.00 | 1.00 | 1.00 |
   II & III & IV | 1.28 (0.37, 4.39) | 0.54 (0.13, 2.18) | 1.88 (0.57, 6.21) | 0.69 (0.19, 2.50) |
Vessel invasion, | Â | Â | Â | Â |
   No | 1.00 | 1.00 | 1.00 | 1.00 |
   Yes | 1.63 (0.38, 6.92) | 1.13 (0.25, 5.17) | 0.14 (0.03, 0.72)* | 0.46 (0.09, |
Nerve invasion | Â | Â | Â | Â |
   No | 1.00 | 1.00 | 1.00 | 1.00 |
   Yes | 1.63 (0.38, 6.92) | 1.29 (0.68, 5.94) | 3.32 (0.92, 12.01) | 0.36, 6.19) |