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Table 2 Correlation between FISH EGFR and immunohistochemicals markers (mEGFR, nEGFR and Cyclin D1)

From: Strong nuclear EGFR expression in colorectal carcinomas is associated with cyclin-D1 but not with gene EGFR amplification

  

EGFR FISH

 

Parameters

Total

≤ 2,0 - 2,49

2,5 - 2,93

≥ 2,94

p - value

mEGFR

    

0.001

   neg./week

49

49

0

0

 

   moderate

64

53

8

3

 

   strong

22

15

2

5

 

nEGFR

    

0.818

   neg./week

9

9

0

0

 

   moderate

49

42

2

5

 

   strong

77

66

8

3

 

Cyclin D1

    

0.876

   neg./week

8

7

1

0

 

   moderate

51

45

1

5

 

   strong

76

65

8

3

 

Total

135

117

   
  1. CRC, colorectal carcinoma
  2. mEGFR, membrane EGFR
  3. nEGFR, nuclear EGFR
  4. test - Spearman rank correlation coefficient