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Table 3 Immunoexpression of Cyclin D1 in relation to EGFR in CRC

From: Strong nuclear EGFR expression in colorectal carcinomas is associated with cyclin-D1 but not with gene EGFR amplification

  

Cyclin D1

 

Parameters

Total

neg./week

moderate

strong

p - value

mEGFR

    

0.672

   neg./week

49

5

19

25

 

   moderate

64

3

21

40

 

   strong

22

0

11

11

 

nEGFR

    

< 0.001

   neg./week

9

6

3

0

 

   moderate

49

1

42

6

 

   strong

77

1

6

70

 

Total

135

8

51

76

 
  1. CRC, colorectal carcinoma
  2. mEGFR, membrane EGFR
  3. nEGFR, nuclear EGFR
  4. test - Spearman rank correlation coefficient