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Table 3 Immunoexpression of Cyclin D1 in relation to EGFR in CRC

From: Strong nuclear EGFR expression in colorectal carcinomas is associated with cyclin-D1 but not with gene EGFR amplification

   Cyclin D1  
Parameters Total neg./week moderate strong p - value
mEGFR      0.672
   neg./week 49 5 19 25  
   moderate 64 3 21 40  
   strong 22 0 11 11  
nEGFR      < 0.001
   neg./week 9 6 3 0  
   moderate 49 1 42 6  
   strong 77 1 6 70  
Total 135 8 51 76  
  1. CRC, colorectal carcinoma
  2. mEGFR, membrane EGFR
  3. nEGFR, nuclear EGFR
  4. test - Spearman rank correlation coefficient