Nuclear beta-catenin overexpression in metastatic sentinel lymph node is associated with synchronous liver metastasis in colorectal cancer

Table 2 Correlation of nuclear beta-catenin expression in SLN(s) with clinicopathological characteristics

Characteristics	Nuclear beta-catenin expression			P*
	n	≤ 50%	> 50%
Gender
Male	247	178	69	0.745
Female	108	76	32
Age
≤ 55	54	15	39	< 0.001
> 55	301	239	62
Tumour localization
Rectum	203	145	58	0.954
Colon	152	109	43
Tumour size (cm)
≤ 5	120	90	30	0.303
≤ 5	235	164	71
Type of tumour
Adenocarcinoma	299	221	78	< 0.001
Mucinous adenocarcinoma	31	11	20
Signet-ring cell carcinoma	16	14	2
Undifferentiated carcinoma	9	8	1
Tumour cell differentiation
Well/moderately differentiated	279	218	61	< 0.001
Poorly differentiated	76	36	40
Tumour invasion depth
T₁	5	5	0	< 0.001
T₂	63	56	7
T₃	252	176	76
T₄	35	17	18
Lymph node metastasis
< 4	123	100	23	0.003
≥ 4	232	154	78
Liver metastasis
Negative	262	231	31	< 0.001
Positive	93	23	70
TNM stage
I	5	5	0	< 0.001
II	20	20	0
III	237	206	31
IV	93	23	70

* P value is the result of χ² test in the same factor, and < 0.05 is considered statistically significant.

ISSN: 1746-1596