Nuclear beta-catenin overexpression in metastatic sentinel lymph node is associated with synchronous liver metastasis in colorectal cancer

Table 3 Clinicopathological risk factors classified according to liver metastasis

Risk factors	Liver Metastasis			P*
	n	Negative	Positive
Gender
Male	247	182	65	0.939
Female	108	80	28
Age
≤ 55	54	22	32	< 0.001
> 55	301	240	61
Tumour localization
Rectum	203	150	53	0.965
Colon	152	112	40
Tumour size (cm)
≤ 5	120	102	18	0.001
> 5	235	160	75
Type of tumour
Adenocarcinoma	299	232	67	0.002
Mucinous adenocarcinoma	31	17	14
Signet-ring cell carcinoma	16	9	7
Undifferentiated carcinoma	9	4	5
Tumour cell differentiation
Well/moderately differentiated	279	236	43	< 0.001
Poorly differentiated	76	26	50
Tumour invasion depth
T₁	5	5	0	0.002
T₂	63	20	1
T₃	252	221	72
T₄	35	25	20
Lymph node metastasis
< 4	123	104	19	0.001
≥ 4	232	158	74
Nuclear beta-catenin expression in SLN(s)
≤ 50%	254	231	23	< 0.001
> 50%	101	31	70

* P value is the result of χ² test in the same factor, and < 0.05 is considered statistically significant.

ISSN: 1746-1596