Tissue expression of squamous cellular carcinoma antigen and Ki67 in hepatocellular carcinoma-correlation with prognosis: A historical prospective study

Table 2 Comparison between 2 groups of HCC patients: positive and negative SCCA immunostaining

Variable	Positive SCAA	Negative SCCA	p value
Age (years)	63.3 ± 10.8	62.4 ± 9.84	NS
HBV infection (positive, %)	27.45	30.00	NS
HCV infection (positive, %)	50.98	40.00	NS
Alcohol (positive, %)	5.88	10.00	NS
Other CLD (positive, %)	74.51	80.00	NS
Serum AFP level (ng/mL)	4853.41 ± 11432.3	736.24 ± 1072.51	0.027
Mean tumor size (cm)	5.13 ± 4.09	6.12 ± 2.71	NS
Tumor number (> 1, %)	84.62	87.88	NS
Tumor differentiation (%)			0.022
Well	37.25	30
Moderate	52.94	20
Poor	3.92	30
TUNEL score	0.24 ± 0.25	0.41 ± 0.30	0.08
Ki67 score	0.10 ± 0.11	0.319 ± 0.22	> 0.0001
AFP immunostaining (negative, %)	60.0	70.7	NS
Liver transplantation (%)	31.37	10.0	NS
Hepatic resection (%)	60.0	54.9	NS
Chemoembolization (%)	60.0	52.94	NS
Survival (months)	39.78 ± 34.78	19.13 ± 20.88	0.026

Abbreviations: HBV = hepatitis B virus; HCV = hepatitis C virus; CLD = chronic liver disease; AFP = alpha feto protein; TUNEL = Terminal Deoxynucleotidyl Transferase dUTP Nick End Labeling

ISSN: 1746-1596