Figure 2

Histomorphology of the decortication specimen. Pleural angiosarcoma with scattered tumor cells in the hemorrhagic background (A). Solid sheets of epithelioid tumor cells can simulate mesothelioma and/or carcinoma (B). Intracytoplasmic lumen containing red blood cells (C, arrowhead) and anastomosing vascular spaces (D) are evidence of endothelial differentiation (hematoxylin-eosin, ×200 [A, D] and ×400 [B, C]).