Figure 2From: Decreased D2-40 and increased p16INK4A immunoreactivities correlate with higher grade of cervical intraepithelial neoplasiaRepresentative examples of p16INK4Aimmunoreactive patterns in the normal cervical tissue and CIN. A: focal p16INK4A immunostaining in CIN1. B: diffuse p16INK4A immunostaining restricted to the lower third of the cervical epithelium in CIN1. C: diffuse p16INK4A immunostaining of more than a third of the cervical epithelium in CIN2 on the left and negative p16INK4A immunostaining in the normal cervical tissue on the right. D: diffuse p16INK4A immunostaining of full thickness of the cervical epithelium in CIN3.Back to article page