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Table 1 Histologic criteria employed in this study for the diagnosis of uterine smooth muscle tumors

From: Diagnostic value of progesterone receptor and p53 expression in uterine smooth muscle tumors

Diagnosis

Tumor cell necrosis

Atypia

MF/10 HPF*

Leiomyosarcoma

Present

Diffuse moderate to severe

Any level

 

Present

None to mild

≥ 10

 

Absent

Diffuse moderate to severe

≥ 10

STUMP

Present

None to mild

< 10

 

Absent

Diffuse moderate to severe

5-9 or atypical mitotic figures

 

Absent

Focal moderate to severe

≥ 5

Atypical leiomyoma

Absent

Focal or diffuse moderate to severe

< 5

Leiomyoma

Absent

None to mild

< 5

  1. *Mitotic figures per 10 High power field